GO enrichment analysis of biologic processes related to the maturation state of the 3 monocyte subsets
| Term . | Count . | % . | P . |
|---|---|---|---|
| Classical monocyte subset | |||
| Apoptosis | |||
| GO:0006916: antiapoptosis | 27 | 3.52 | 5.32E-06 |
| GO:0043066: negative regulation of apoptosis | 35 | 4.56 | 7.91E-05 |
| GO:0042981: regulation of apoptosis | 61 | 7.94 | 3.39E-04 |
| GO:0006915: apoptosis | 43 | 5.60 | 8.33E-03 |
| Proliferation | |||
| GO:0008284: positive regulation of cell proliferation | 34 | 4.43 | 2.64E-03 |
| GO:0042127: regulation of cell proliferation | 55 | 7.16 | 4.12E-03 |
| GO:0008283: cell proliferation | 34 | 4.43 | 5.77E-03 |
| GO:0008285: negative regulation of cell proliferation | 26 | 3.39 | 3.91E-02 |
| Intermediate monocyte subset | |||
| Apoptosis | |||
| GO:0042981: regulation of apoptosis | 12 | 10.26 | 3.28E-02 |
| GO:0008624: induction of apoptosis by extracellular signals | 4 | 3.42 | 4.89E-02 |
| Cell differentiation | |||
| GO:0045596: negative regulation of cell differentiation | 7 | 5.98 | 5.05E-03 |
| Nonclassical monocyte subset | |||
| Apoptosis | |||
| GO:0042981: regulation of apoptosis | 51 | 10.32 | 4.91E-06 |
| GO:0006917: induction of apoptosis | 26 | 5.26 | 3.58E-05 |
| GO:0043065: positive regulation of apoptosis | 31 | 6.28 | 5.31E-05 |
| GO:0008624: induction of apoptosis by extracellular signals | 14 | 2.83 | 6.20E-05 |
| GO:0006915: apoptosis | 35 | 7.09 | 8.86E-04 |
| GO:0043066: negative regulation of apoptosis | 21 | 4.25 | 1.07E-02 |
| GO:0006916: antiapoptosis | 13 | 2.63 | 3.48E-02 |
| Proliferation | |||
| GO:0042127: regulation of cell proliferation | 50 | 10.12 | 5.75E-06 |
| GO:0008285: negative regulation of cell proliferation | 25 | 5.06 | 6.17E-04 |
| GO:0008284: positive regulation of cell proliferation | 24 | 4.86 | 7.38E-03 |
| Cell differentiation | |||
| GO:0045637: regulation of myeloid cell differentiation | 7 | 1.42 | 2.49E-02 |
| GO:0002521: leukocyte differentiation | 10 | 2.02 | 2.56E-02 |
| GO:0030098: lymphocyte differentiation | 8 | 1.62 | 4.83E-02 |
| Term . | Count . | % . | P . |
|---|---|---|---|
| Classical monocyte subset | |||
| Apoptosis | |||
| GO:0006916: antiapoptosis | 27 | 3.52 | 5.32E-06 |
| GO:0043066: negative regulation of apoptosis | 35 | 4.56 | 7.91E-05 |
| GO:0042981: regulation of apoptosis | 61 | 7.94 | 3.39E-04 |
| GO:0006915: apoptosis | 43 | 5.60 | 8.33E-03 |
| Proliferation | |||
| GO:0008284: positive regulation of cell proliferation | 34 | 4.43 | 2.64E-03 |
| GO:0042127: regulation of cell proliferation | 55 | 7.16 | 4.12E-03 |
| GO:0008283: cell proliferation | 34 | 4.43 | 5.77E-03 |
| GO:0008285: negative regulation of cell proliferation | 26 | 3.39 | 3.91E-02 |
| Intermediate monocyte subset | |||
| Apoptosis | |||
| GO:0042981: regulation of apoptosis | 12 | 10.26 | 3.28E-02 |
| GO:0008624: induction of apoptosis by extracellular signals | 4 | 3.42 | 4.89E-02 |
| Cell differentiation | |||
| GO:0045596: negative regulation of cell differentiation | 7 | 5.98 | 5.05E-03 |
| Nonclassical monocyte subset | |||
| Apoptosis | |||
| GO:0042981: regulation of apoptosis | 51 | 10.32 | 4.91E-06 |
| GO:0006917: induction of apoptosis | 26 | 5.26 | 3.58E-05 |
| GO:0043065: positive regulation of apoptosis | 31 | 6.28 | 5.31E-05 |
| GO:0008624: induction of apoptosis by extracellular signals | 14 | 2.83 | 6.20E-05 |
| GO:0006915: apoptosis | 35 | 7.09 | 8.86E-04 |
| GO:0043066: negative regulation of apoptosis | 21 | 4.25 | 1.07E-02 |
| GO:0006916: antiapoptosis | 13 | 2.63 | 3.48E-02 |
| Proliferation | |||
| GO:0042127: regulation of cell proliferation | 50 | 10.12 | 5.75E-06 |
| GO:0008285: negative regulation of cell proliferation | 25 | 5.06 | 6.17E-04 |
| GO:0008284: positive regulation of cell proliferation | 24 | 4.86 | 7.38E-03 |
| Cell differentiation | |||
| GO:0045637: regulation of myeloid cell differentiation | 7 | 1.42 | 2.49E-02 |
| GO:0002521: leukocyte differentiation | 10 | 2.02 | 2.56E-02 |
| GO:0030098: lymphocyte differentiation | 8 | 1.62 | 4.83E-02 |