Multivariate analysis of OS
| Variable . | Total (n = 779) . | Standard-risk (n = 492) . | High-risk (n = 262) . | |||
|---|---|---|---|---|---|---|
| HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | |
| Donor type | ||||||
| 8/8 MUD | 1.00 | 1.00 | 1.00 | |||
| RD/1AG-MM-GVH | 1.49 (1.19-1.86) | < .001 | 1.72 (1.24-2.39) | .001 | 1.30 (0.96-1.76) | .095 |
| Age, y | ||||||
| ≤ 50 | 1.00 | 1.00 | ||||
| > 50 | 1.44 (1.16-1.79) | .001 | 1.55 (1.13-2.15) | .007 | ||
| Performance status | ||||||
| 0/1 | 1.00 | 1.00 | ||||
| 2/3/4 | 1.79 (1.30-2.48) | < .001 | 1.76 (1.24-2.52) | .002 | ||
| Disease risk | ||||||
| Standard | 1.00 | |||||
| High | 2.41 (1.92-3.03) | < .001 | ||||
| Unknown | 1.38 (0.82-2.33) | .227 | ||||
| Variable . | Total (n = 779) . | Standard-risk (n = 492) . | High-risk (n = 262) . | |||
|---|---|---|---|---|---|---|
| HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | |
| Donor type | ||||||
| 8/8 MUD | 1.00 | 1.00 | 1.00 | |||
| RD/1AG-MM-GVH | 1.49 (1.19-1.86) | < .001 | 1.72 (1.24-2.39) | .001 | 1.30 (0.96-1.76) | .095 |
| Age, y | ||||||
| ≤ 50 | 1.00 | 1.00 | ||||
| > 50 | 1.44 (1.16-1.79) | .001 | 1.55 (1.13-2.15) | .007 | ||
| Performance status | ||||||
| 0/1 | 1.00 | 1.00 | ||||
| 2/3/4 | 1.79 (1.30-2.48) | < .001 | 1.76 (1.24-2.52) | .002 | ||
| Disease risk | ||||||
| Standard | 1.00 | |||||
| High | 2.41 (1.92-3.03) | < .001 | ||||
| Unknown | 1.38 (0.82-2.33) | .227 | ||||
Only variables that remained after backward selection in the multivariate analysis are shown.