Prevalence of thrombophilias at baseline
| . | Negative group . | Constitutional thrombophilia group . | aPLAb group . |
|---|---|---|---|
| LA | |||
| Positive for LA | 0 | 0 | 319 (61.7%) |
| LA: activity | 0.99 (0.09) [0.82-1.20] | 1.02 (0.09) [0.79-1.21] | 1.42 (0.78) [0.79-2.68] |
| Anti-cardiolipin IgG | |||
| Positive for aCL-G | 0 | 0 | 244 (47.2%) |
| aCL-G titer, μg/ml | 0.39 (0.21) [0.05-0.84] | 0.41 (0.22)[0.07-0.84] | 0.70 (1.37) [0.05-7.1] |
| Anti-cardiolipin IgM | |||
| Positive for aCL-M | 0 | 0 | 372 (71.9%) |
| aCL-M titer, μg/ml | 0.54 (0.32) [0.08-1.35] | 0.51 (0.29) [0.05-1.34] | 1.60 (1.55) [0.05-18.1] |
| Anti–β2-glycoprotein I IgG | |||
| Positive for aβ2GP1-G | 0 | 0 | 114 (22.1%) |
| aβ2GP1-G titer, μg/ml | 0.23 (0.14) [0.05-0.86] | 0.26 (0.18) [0.02-0.84] | 0.57 (0.55) [0.03-6.9] |
| Anti–β2-glycoprotein I IgM | |||
| Positive for aβ2GP1-M | 0 | 0 | 210 (40.6%) |
| aβ2GP1-M titer, μg/ml | 0.41 (0.24) [0.04-0.98] | 0.47 (0.34) [0.02-0.98] | 0.72 (0.85) [0.05-19.4] |
| Categories of positive aPLAb | |||
| I | 383 (74.1%) | ||
| IIa | 31 (6%) | ||
| IIb | 103 (19.9%) | ||
| IIc | 0 | ||
| LA + aCL + aβ2GP1 | 149 (28.8%) | ||
| Constitutional thrombophilias | |||
| F5 6025 or F2 rs1799963 | 0 | 279 (100%) | 17 (3.3%) |
| . | Negative group . | Constitutional thrombophilia group . | aPLAb group . |
|---|---|---|---|
| LA | |||
| Positive for LA | 0 | 0 | 319 (61.7%) |
| LA: activity | 0.99 (0.09) [0.82-1.20] | 1.02 (0.09) [0.79-1.21] | 1.42 (0.78) [0.79-2.68] |
| Anti-cardiolipin IgG | |||
| Positive for aCL-G | 0 | 0 | 244 (47.2%) |
| aCL-G titer, μg/ml | 0.39 (0.21) [0.05-0.84] | 0.41 (0.22)[0.07-0.84] | 0.70 (1.37) [0.05-7.1] |
| Anti-cardiolipin IgM | |||
| Positive for aCL-M | 0 | 0 | 372 (71.9%) |
| aCL-M titer, μg/ml | 0.54 (0.32) [0.08-1.35] | 0.51 (0.29) [0.05-1.34] | 1.60 (1.55) [0.05-18.1] |
| Anti–β2-glycoprotein I IgG | |||
| Positive for aβ2GP1-G | 0 | 0 | 114 (22.1%) |
| aβ2GP1-G titer, μg/ml | 0.23 (0.14) [0.05-0.86] | 0.26 (0.18) [0.02-0.84] | 0.57 (0.55) [0.03-6.9] |
| Anti–β2-glycoprotein I IgM | |||
| Positive for aβ2GP1-M | 0 | 0 | 210 (40.6%) |
| aβ2GP1-M titer, μg/ml | 0.41 (0.24) [0.04-0.98] | 0.47 (0.34) [0.02-0.98] | 0.72 (0.85) [0.05-19.4] |
| Categories of positive aPLAb | |||
| I | 383 (74.1%) | ||
| IIa | 31 (6%) | ||
| IIb | 103 (19.9%) | ||
| IIc | 0 | ||
| LA + aCL + aβ2GP1 | 149 (28.8%) | ||
| Constitutional thrombophilias | |||
| F5 6025 or F2 rs1799963 | 0 | 279 (100%) | 17 (3.3%) |
Quantitative data are given as median (interquartile range) [range] values and qualitative data as number (percentage) values.