Retrospective clinical scoring before and after rituximab administration
| Parameter (values assigned) . | Patient 1 . | Patient 2 . | Patient 3 . | Patient 4 . | ||||
|---|---|---|---|---|---|---|---|---|
| Before . | After . | Before . | After . | Before . | After . | Before . | After . | |
| Constitutional (fever, weight loss, malaise: 1 point each) | 0 (unknown) | 0 | 2 (fever, malaise) | 0 | 2 (fever, weight loss) | 0 | 2 (weight loss, malaise) | 0 |
| Clinical infection (0, healing of sinus tract; 1, stable lesion; 2, development of sinus tract) | 2 | 0 | 0 | 0 | 2 | 0 | 2 | 0 |
| Positive blood cultures (0, negative; 2, positive) | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
| Radiographic change (0, resolved; 1, improvement; 2, stable; 3, progression) | 3 | 1 | 3 | 1 | 3 | 1 | 3 | 1 |
| Hypergammaglobulinemia (0, normal; 1, elevated) | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
| Total score | 8 | 1 | 8 | 1 | 8 | 1 | 8 | 1 |
| Parameter (values assigned) . | Patient 1 . | Patient 2 . | Patient 3 . | Patient 4 . | ||||
|---|---|---|---|---|---|---|---|---|
| Before . | After . | Before . | After . | Before . | After . | Before . | After . | |
| Constitutional (fever, weight loss, malaise: 1 point each) | 0 (unknown) | 0 | 2 (fever, malaise) | 0 | 2 (fever, weight loss) | 0 | 2 (weight loss, malaise) | 0 |
| Clinical infection (0, healing of sinus tract; 1, stable lesion; 2, development of sinus tract) | 2 | 0 | 0 | 0 | 2 | 0 | 2 | 0 |
| Positive blood cultures (0, negative; 2, positive) | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
| Radiographic change (0, resolved; 1, improvement; 2, stable; 3, progression) | 3 | 1 | 3 | 1 | 3 | 1 | 3 | 1 |
| Hypergammaglobulinemia (0, normal; 1, elevated) | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
| Total score | 8 | 1 | 8 | 1 | 8 | 1 | 8 | 1 |