Causes of death in adult AML patients who underwent HLA-identical sibling (MRD) HCT or 8/8 or 7/8 MUD HCT
| Cause, n (%) . | MRD . | 8/8 MUD . | 7/8 MUD . |
|---|---|---|---|
| Missing | 6 (1.5) | 7 (< 1) | 3 (1) |
| Graft rejection | 1 (< 1) | 8 (1) | 0 |
| Infection | 39 (10) | 109 (14) | 55 (20) |
| Interstitial pneumonitis | 7 (2) | 23 (3) | 10 (4) |
| ARDS | 4 (1) | 20 (3) | 2 (< 1) |
| GVHD | 44 (11) | 98 (13) | 44 (16) |
| Primary disease | 216 (54) | 362 (47) | 102 (37) |
| Organ failure | 40 (10) | 63 (8) | 26 (9) |
| Secondary malignancy | 5 (1) | 5 (< 1) | 1 (< 1) |
| Hemorrhage | 9 (2) | 10 (1) | 2 (< 1) |
| Accidental death | 1 (< 1) | 1 (< 1) | 0 |
| Vascular | 2 (< 1) | 4 (< 1) | 3 (1) |
| Toxicity | 0 | 25 (3) | 5 (2) |
| Other cause | 23 (6) | 38 (5) | 22 (8) |
| Total | 397 | 773 | 275 |
| Cause, n (%) . | MRD . | 8/8 MUD . | 7/8 MUD . |
|---|---|---|---|
| Missing | 6 (1.5) | 7 (< 1) | 3 (1) |
| Graft rejection | 1 (< 1) | 8 (1) | 0 |
| Infection | 39 (10) | 109 (14) | 55 (20) |
| Interstitial pneumonitis | 7 (2) | 23 (3) | 10 (4) |
| ARDS | 4 (1) | 20 (3) | 2 (< 1) |
| GVHD | 44 (11) | 98 (13) | 44 (16) |
| Primary disease | 216 (54) | 362 (47) | 102 (37) |
| Organ failure | 40 (10) | 63 (8) | 26 (9) |
| Secondary malignancy | 5 (1) | 5 (< 1) | 1 (< 1) |
| Hemorrhage | 9 (2) | 10 (1) | 2 (< 1) |
| Accidental death | 1 (< 1) | 1 (< 1) | 0 |
| Vascular | 2 (< 1) | 4 (< 1) | 3 (1) |
| Toxicity | 0 | 25 (3) | 5 (2) |
| Other cause | 23 (6) | 38 (5) | 22 (8) |
| Total | 397 | 773 | 275 |
ARDS indicates acute respiratory distress syndrome.