Table 5

Relationship between DIPSS covariate and HCT outcomes

HCT outcome*HR95% CIP
Overall mortality    
    Age 1.67 0.67-4.16 .27 
    Hemoglobin 2.78 1.55-4.99 < .001 
    Leukocyte count 0.94 0.53-1.63 .81 
    Peripheral blasts 1.78 1.09-2.90 .02 
    Constitutional symptoms 1.43 0.88-2.32 .15 
Relapse or death    
    Age 1.51 0.61-3.75 .37 
    Hemoglobin 2.51 1.44-4.36 .001 
    Leukocyte count 0.94 0.55-1.61 .81 
    Peripheral blasts 1.71 1.07-2.73 .02 
    Constitutional symptoms 1.43 0.89-2.30 .14 
Relapse    
    Age 0 0 .99 
    Hemoglobin 1.13 0.45-2.88 .80 
    Leukocyte count 1.84 0.73-4.69 .20 
    Peripheral blasts 2.42 0.91-6.40 .07 
    Constitutional symptoms 1.08 0.42-2.78 .88 
NRM    
    Age 1.99 0.79-5.00 .14 
    Hemoglobin 3.59 1.76-7.32 < .001 
    Leukocyte count 0.70 0.35-1.38 .30 
    Peripheral blasts 1.53 0.89-2.61 .12 
    Constitutional symptoms 1.58 0.91-2.73 .10 
HCT outcome*HR95% CIP
Overall mortality    
    Age 1.67 0.67-4.16 .27 
    Hemoglobin 2.78 1.55-4.99 < .001 
    Leukocyte count 0.94 0.53-1.63 .81 
    Peripheral blasts 1.78 1.09-2.90 .02 
    Constitutional symptoms 1.43 0.88-2.32 .15 
Relapse or death    
    Age 1.51 0.61-3.75 .37 
    Hemoglobin 2.51 1.44-4.36 .001 
    Leukocyte count 0.94 0.55-1.61 .81 
    Peripheral blasts 1.71 1.07-2.73 .02 
    Constitutional symptoms 1.43 0.89-2.30 .14 
Relapse    
    Age 0 0 .99 
    Hemoglobin 1.13 0.45-2.88 .80 
    Leukocyte count 1.84 0.73-4.69 .20 
    Peripheral blasts 2.42 0.91-6.40 .07 
    Constitutional symptoms 1.08 0.42-2.78 .88 
NRM    
    Age 1.99 0.79-5.00 .14 
    Hemoglobin 3.59 1.76-7.32 < .001 
    Leukocyte count 0.70 0.35-1.38 .30 
    Peripheral blasts 1.53 0.89-2.61 .12 
    Constitutional symptoms 1.58 0.91-2.73 .10 
*

Referent category is low risk for each covariate.

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