Characteristics of the GHS population sample by stratification for values above and below the reference limits for MPV (N = 14 968)
| Characteristic . | Females . | Males . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ≤95th percentile (n = 7012) . | >95th percentile (n = 385) . | P . | ≤95th percentile (n = 7060) . | >95th percentile (n = 511) . | P . | |||||
| Median . | IQR . | Median . | IQR . | Median . | IQR . | Median . | IQR . | |||
| Age (y) | 55.0 | 45.0-64.0 | 56.0 | 46.0-65.0 | .068 | 55.0 | 46.0-65.0 | 58.0 | 47.0-66.0 | .0023 |
| WBC (× 109/L) | 6.94 | 5.90-8.30 | 7.37 | 6.04-8.61 | .00086 | 6.84 | 5.74-8.20 | 7.10 | 6.07-8.37 | .0025 |
| Platelets (× 109/L) | 289.0 | 249.0-332.0 | 230.0 | 197.0-265.3 | <.0001 | 255.0 | 219.0-296.0 | 207.5 | 177.4-241.0 | <.0001 |
| CRP (mg/L) | 1.60 | 0.57-3.50 | 1.80 | 0.85-3.60 | .18 | 1.50 | 0.51-2.90 | 1.70 | 0.81-3.30 | .0018 |
| Fibrinogen (mg/dL) | 325.0 | 283.0-380.0 | 332.0 | 293.0-387.0 | .071 | 315.0 | 272.0-369.0 | 327.0 | 285.0-388.0 | .00045 |
| Glucose (mg/dL) | 90.0 | 84.0-96.0 | 89.2 | 83.7-98.0 | .86 | 93.0 | 87.0-100.2 | 94.0 | 87.0-103.0 | .047 |
| LDL (mg/dL) | 137.0 | 114.0-162.0 | 131.9 | 108.9-157.0 | .013 | 137.0 | 115.0-160.0 | 132.0 | 109.0-161.9 | .0094 |
| HDL (mg/dL) | 63.0 | 53.6-74.0 | 61.0 | 51.0-72.0 | .012 | 49.0 | 42.0-57.0 | 48.0 | 40.0-55.0 | .0065 |
| Cholesterol (mg/dL) | 223 | 197-252 | 216 | 188-247 | .0032 | 215.0 | 189.0-241.0 | 210.0 | 182.0-241.0 | .043 |
| Triglycerides (mg/dL) | 96.0 | 72.0-129.0 | 102.0 | 75.2-134.0 | .068 | 117.0 | 85.0-164.0 | 122.0 | 89.0-171.0 | .0091 |
| Characteristic . | Females . | Males . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ≤95th percentile (n = 7012) . | >95th percentile (n = 385) . | P . | ≤95th percentile (n = 7060) . | >95th percentile (n = 511) . | P . | |||||
| Median . | IQR . | Median . | IQR . | Median . | IQR . | Median . | IQR . | |||
| Age (y) | 55.0 | 45.0-64.0 | 56.0 | 46.0-65.0 | .068 | 55.0 | 46.0-65.0 | 58.0 | 47.0-66.0 | .0023 |
| WBC (× 109/L) | 6.94 | 5.90-8.30 | 7.37 | 6.04-8.61 | .00086 | 6.84 | 5.74-8.20 | 7.10 | 6.07-8.37 | .0025 |
| Platelets (× 109/L) | 289.0 | 249.0-332.0 | 230.0 | 197.0-265.3 | <.0001 | 255.0 | 219.0-296.0 | 207.5 | 177.4-241.0 | <.0001 |
| CRP (mg/L) | 1.60 | 0.57-3.50 | 1.80 | 0.85-3.60 | .18 | 1.50 | 0.51-2.90 | 1.70 | 0.81-3.30 | .0018 |
| Fibrinogen (mg/dL) | 325.0 | 283.0-380.0 | 332.0 | 293.0-387.0 | .071 | 315.0 | 272.0-369.0 | 327.0 | 285.0-388.0 | .00045 |
| Glucose (mg/dL) | 90.0 | 84.0-96.0 | 89.2 | 83.7-98.0 | .86 | 93.0 | 87.0-100.2 | 94.0 | 87.0-103.0 | .047 |
| LDL (mg/dL) | 137.0 | 114.0-162.0 | 131.9 | 108.9-157.0 | .013 | 137.0 | 115.0-160.0 | 132.0 | 109.0-161.9 | .0094 |
| HDL (mg/dL) | 63.0 | 53.6-74.0 | 61.0 | 51.0-72.0 | .012 | 49.0 | 42.0-57.0 | 48.0 | 40.0-55.0 | .0065 |
| Cholesterol (mg/dL) | 223 | 197-252 | 216 | 188-247 | .0032 | 215.0 | 189.0-241.0 | 210.0 | 182.0-241.0 | .043 |
| Triglycerides (mg/dL) | 96.0 | 72.0-129.0 | 102.0 | 75.2-134.0 | .068 | 117.0 | 85.0-164.0 | 122.0 | 89.0-171.0 | .0091 |
Categories are based on the 95th percentile of MVP in the reference group.
HDL, high-density lipoprotein; IQR, interquartile range; LDL, low-density lipoprotein.