Amino acid sequences of CDRs within the VH and VL regions from ephrinB2-specific scFv clones
| scFv clones . | CDR1 . | CDR2 . | CDR3 . |
|---|---|---|---|
| VH | |||
| A1 | SYWIG | YPGDSDTRYGPSFQG | HPAAAGTHDGFDI |
| B11 | DYYIH | WMNPSSGNTGYAQKFQGR | DITGTATGFDY |
| E4 | SYAMH | VISYDGSNKYYADSVKGR | DYGGYRYGYFDY |
| 2B1 | DYAMH | GISWNSGSIGYADSVKGR | GHRTSDAFDI |
| VL | |||
| A1 | TGSSSNIGAGYDVH | GNSNRPS | AAWDDSLNGL |
| B11 | RSSQSLLHSNGYNYLD | GSNRAS | MQGLLSPVT |
| E4 | TGGGSNIGAGHDVH | SNTNRP | QSYDSSLSGWV |
| 2B1 | GGDSIGLKSVH | SDSDRPS | QVWDSSSDHMV |
| scFv clones . | CDR1 . | CDR2 . | CDR3 . |
|---|---|---|---|
| VH | |||
| A1 | SYWIG | YPGDSDTRYGPSFQG | HPAAAGTHDGFDI |
| B11 | DYYIH | WMNPSSGNTGYAQKFQGR | DITGTATGFDY |
| E4 | SYAMH | VISYDGSNKYYADSVKGR | DYGGYRYGYFDY |
| 2B1 | DYAMH | GISWNSGSIGYADSVKGR | GHRTSDAFDI |
| VL | |||
| A1 | TGSSSNIGAGYDVH | GNSNRPS | AAWDDSLNGL |
| B11 | RSSQSLLHSNGYNYLD | GSNRAS | MQGLLSPVT |
| E4 | TGGGSNIGAGHDVH | SNTNRP | QSYDSSLSGWV |
| 2B1 | GGDSIGLKSVH | SDSDRPS | QVWDSSSDHMV |
CDR indicates complementarity determining region; VH, heavy-chain V region; VL, light-chain V region; and scFv, single-chain Fv.