ITT and per-protocol analyses
| . | PFS . | FFS . | EFS . | OS . | ATFS . |
|---|---|---|---|---|---|
| ITT principle (ITT population, whatever the treatment) | +++ | − | − | +++ | − |
| Per-protocol analyses | |||||
| Within the ITT population, and according to study therapy | Optional | + | + | Optional | + |
| Within subgroups | Optional |
| . | PFS . | FFS . | EFS . | OS . | ATFS . |
|---|---|---|---|---|---|
| ITT principle (ITT population, whatever the treatment) | +++ | − | − | +++ | − |
| Per-protocol analyses | |||||
| Within the ITT population, and according to study therapy | Optional | + | + | Optional | + |
| Within subgroups | Optional |
Optional indicates that these analyses are not recommended by ELN (if these analyses are required in some studies, reasons and definitions have to be explicitly provided) +++, highly recommended; +, to be considered; and −, not relevant, based on ELN definitions.