Outcomes
| . | −G-CSF, no. (%) (n = 461) . | +G-CSF, no. (%) (n = 456) . | P . | OR or HR (95% CI) . |
|---|---|---|---|---|
| Death within 30 d | ||||
| Cycle 1 | 50 (11) | 39 (9) | .27* | |
| Cycle 2 | 27 (7) | 12 (3) | .02* | |
| Complete remission | 354 (77) | 370 (81) | .11 | OR = 1.30 (0.95-1.79) |
| Early (after cycle 1) | 273 (59) | 291 (64) | ||
| Late (after cycle 2) | 81 (18) | 79 (17) | ||
| Relapse† | 155 (36) | 156 (34) | .77 | HR = 0.97 (0.77-1.21) |
| Death in CR1† | 41 (9) | 45 (10) | .80 | HR = 1.06 (0.69-1.61) |
| EFS‡ | 303 (31) | 286 (37) | .29 | HR = 0.92 (0.78-1.08) |
| OS§ | 256 (40) | 253 (43) | .88 | HR = 0.99 (0.83-1.17) |
| . | −G-CSF, no. (%) (n = 461) . | +G-CSF, no. (%) (n = 456) . | P . | OR or HR (95% CI) . |
|---|---|---|---|---|
| Death within 30 d | ||||
| Cycle 1 | 50 (11) | 39 (9) | .27* | |
| Cycle 2 | 27 (7) | 12 (3) | .02* | |
| Complete remission | 354 (77) | 370 (81) | .11 | OR = 1.30 (0.95-1.79) |
| Early (after cycle 1) | 273 (59) | 291 (64) | ||
| Late (after cycle 2) | 81 (18) | 79 (17) | ||
| Relapse† | 155 (36) | 156 (34) | .77 | HR = 0.97 (0.77-1.21) |
| Death in CR1† | 41 (9) | 45 (10) | .80 | HR = 1.06 (0.69-1.61) |
| EFS‡ | 303 (31) | 286 (37) | .29 | HR = 0.92 (0.78-1.08) |
| OS§ | 256 (40) | 253 (43) | .88 | HR = 0.99 (0.83-1.17) |
OR indicates odds ratio; and HR, hazard ratio.
P value from Fisher exact test. Other P values from likelihood ratio test with logistic regression or Cox regression.
Number and 5-year competing risk probability.
Number of events (no CR, relapse, or death in CR1) and 5-year EFS %.
Number of deaths and 5-year OS %.