Toxicities attributable to RdC (n = 37)
| Toxicity, n (%) . | Any grade* . | Grade 3/4* . | Grade 5 . |
|---|---|---|---|
| Neutropenia | 9 (24%) | 9 (24%) | |
| Thrombocytopenia | 5 (14%) | 3 (8%) | |
| Anemia | 6 (16%) | 4 (11%) | |
| Cardiovascular | 3 (8%) | 1 (3%) | 2 (5%) |
| Fever/infection | 9 (24%) | 5 (14%) | |
| Fatigue | 19 (52%) | 5 (14%) | |
| Rash | 13 (35%) | 2 (5%) | |
| Deep vein thrombosis | 2 (5%) | 2 (5%) | |
| Diarrhea | 5 (15%) | 1 (3%) | |
| Peripheral edema | 8 (22%) | ||
| Increased creatinine | 6 (17%) | ||
| Constipation | 6 (17%) | ||
| Hypotension/orthostasis | 6 (17%) | ||
| Hyponatremia | 6 (17%) | ||
| Myalgia | 3 (8%) | ||
| Peripheral neuropathy† | 4 (11%) | ||
| Myalgia | 1 (3%) | ||
| Hypocalcemia | 1 (3%) |
| Toxicity, n (%) . | Any grade* . | Grade 3/4* . | Grade 5 . |
|---|---|---|---|
| Neutropenia | 9 (24%) | 9 (24%) | |
| Thrombocytopenia | 5 (14%) | 3 (8%) | |
| Anemia | 6 (16%) | 4 (11%) | |
| Cardiovascular | 3 (8%) | 1 (3%) | 2 (5%) |
| Fever/infection | 9 (24%) | 5 (14%) | |
| Fatigue | 19 (52%) | 5 (14%) | |
| Rash | 13 (35%) | 2 (5%) | |
| Deep vein thrombosis | 2 (5%) | 2 (5%) | |
| Diarrhea | 5 (15%) | 1 (3%) | |
| Peripheral edema | 8 (22%) | ||
| Increased creatinine | 6 (17%) | ||
| Constipation | 6 (17%) | ||
| Hypotension/orthostasis | 6 (17%) | ||
| Hyponatremia | 6 (17%) | ||
| Myalgia | 3 (8%) | ||
| Peripheral neuropathy† | 4 (11%) | ||
| Myalgia | 1 (3%) | ||
| Hypocalcemia | 1 (3%) |