Table 2 Summary of body weight... | American Society of Hematology

Table 2

Summary of body weight development, hematology, and serum chemistry of ADAMTS13 KO mice receiving treatment with rhADAMTS13 before or after challenge with rhVWF

Variable	Time point, d	Prophylactic treatment: 200 U/kg rhADAMTS13* + 2000 U/kg rhVWF†		Therapeutic treatment: 2000 U/kg rhVWF† + 320 U/kg rhADAMTS13*
				After 15 min		After 30 min		After 180 min
		Mean	n	Mean	n	Mean	n	mean	n
Body weight, Δ%	0-1	−0.7	6	−2.5	6	−3.8	6	−3.0	6
Platelets, × 10³/μL	1	1263	6	970	6	805	6	370	6
Hematocrit, %	1	36.9	6	39.3	6	38.3	6	34.1	6
LDH, U/L	1	296	6	256	6	222	6	206	6

Variable	Time point, d	Prophylactic treatment: 200 U/kg rhADAMTS13* + 2000 U/kg rhVWF†		Therapeutic treatment: 2000 U/kg rhVWF† + 320 U/kg rhADAMTS13*
				After 15 min		After 30 min		After 180 min
		Mean	n	Mean	n	Mean	n	mean	n
Body weight, Δ%	0-1	−0.7	6	−2.5	6	−3.8	6	−3.0	6
Platelets, × 10³/μL	1	1263	6	970	6	805	6	370	6
Hematocrit, %	1	36.9	6	39.3	6	38.3	6	34.1	6
LDH, U/L	1	296	6	256	6	222	6	206	6

U rADAMTS13 = FRETS-U rhADAMTS13.

U rhVWF = VWF:RCoU rhVWF.