Causes of death by treatment group
| . | 8/8 PBPCs (%) . | 7/8 PBPCs (%) . | dUCB-TCF (%) . | dUCB-other (%) . |
|---|---|---|---|---|
| No. of deaths | 189 | 75 | 70 | 31 |
| Graft failure | 2 (1) | 3 (4) | ||
| Recurrent leukemia | 100 (53) | 30 (40) | 35 (50) | 4 (13) |
| GVHD | 22 (12) | 9 (12) | 3 (4) | 5 (16) |
| Interstitial pneumonitis/ARDS | 5 (3) | 2 (3) | 5 (7) | |
| Infection | 25 (13) | 18 (24) | 11 (16) | 9 (29) |
| Organ failure | 21 (12) | 6 (8) | 5 (7) | 9 (29) |
| Pulmonary emboli | 3 (2) | 1 (1) | ||
| Hemorrhage | 4 (2) | 3 (4) | 3 (4) | |
| Metabolic (electrolyte abnormalities) | 2 (1) | |||
| Second malignant neoplasm | 3 (2) | 1 (3) | ||
| Accidental | 2 (6) | |||
| Not reported | 2 (1) | 6 (8) | 5 (7) | 1 (3) |
| . | 8/8 PBPCs (%) . | 7/8 PBPCs (%) . | dUCB-TCF (%) . | dUCB-other (%) . |
|---|---|---|---|---|
| No. of deaths | 189 | 75 | 70 | 31 |
| Graft failure | 2 (1) | 3 (4) | ||
| Recurrent leukemia | 100 (53) | 30 (40) | 35 (50) | 4 (13) |
| GVHD | 22 (12) | 9 (12) | 3 (4) | 5 (16) |
| Interstitial pneumonitis/ARDS | 5 (3) | 2 (3) | 5 (7) | |
| Infection | 25 (13) | 18 (24) | 11 (16) | 9 (29) |
| Organ failure | 21 (12) | 6 (8) | 5 (7) | 9 (29) |
| Pulmonary emboli | 3 (2) | 1 (1) | ||
| Hemorrhage | 4 (2) | 3 (4) | 3 (4) | |
| Metabolic (electrolyte abnormalities) | 2 (1) | |||
| Second malignant neoplasm | 3 (2) | 1 (3) | ||
| Accidental | 2 (6) | |||
| Not reported | 2 (1) | 6 (8) | 5 (7) | 1 (3) |
PBPC indicates peripheral blood progenitor cell; and ARDS, acute respiratory distress syndrome.