Table 3

Toxicities: grade 3 or greater nonhematologic toxicities regardless of attribution during cycles 1-2

Infections/febrile neutropenia11 patients
    Pneumonia 
    Cellulitis 
    Bloodstream 
    Neutropenic fever 
Organ toxicities* 23 events 
    Neurotoxicity 
    Gastrointestinal 
    Pulmonary 
    DVT/PE 
    Hyperglycemia 
    Confusion 
    Rash 
    Acute renal failure 
    Atrial fibrillation 
    Syncope 
Death 4 patients 
    Infection 
    Pulmonary fibrosis 
    Disease 
Infections/febrile neutropenia11 patients
    Pneumonia 
    Cellulitis 
    Bloodstream 
    Neutropenic fever 
Organ toxicities* 23 events 
    Neurotoxicity 
    Gastrointestinal 
    Pulmonary 
    DVT/PE 
    Hyperglycemia 
    Confusion 
    Rash 
    Acute renal failure 
    Atrial fibrillation 
    Syncope 
Death 4 patients 
    Infection 
    Pulmonary fibrosis 
    Disease 

DVT indicates deep-vein thrombosis; and PE, pulmonary embolism.

*

Toxicities that recurred in individual patients in both cycles 1 and 2 are listed as 2 events.

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