Comparative of clinical characteristics of patients at baseline according to the SNP-A–detected lesion nature
| . | Deletion(7), n = 63 (A) . | Deletion(7q), n = 72 (B) . | UPD(7q), n = 26 (C) . | P (only significant comparisons reported) . |
|---|---|---|---|---|
| Median age, y (range) | 58 (27-70) | 64 (56-72) | 68 (63.2-77) | A vs B (P = .01) A vs C (P = .009) |
| Sex | ||||
| Male, % | 59 | 56 | 57 | |
| Female, % | 41 | 44 | 43 | |
| White blood cell count, × 109/L, median (IQR) | 5.5 (2.7-25.7) | 4.3 (2.1-13.5) | 10.5 (8.1-37.9) | C vs A (P = .028) C vs B (P = .01) |
| Hemoglobin, g/dL, mean ± SD | 9.1 ± 1.9 | 9.2 (8.9-10) | 9.1 ± 2.1 | |
| Mean corpuscular volume, median (IQR) | 91 (85-99) | 90 (86-104.8) | 90 (85-103) | |
| Platelets, × 109/L, median (IQR) | 47 (22-71) | 50 (24-86) | 46 (20.2-146.2) | |
| BM cellularity, median (%) | 35 (22-61) | 75 (45-90) | 76(55-100) | A vs B (P = .03) A vs C (P = .036) |
| . | Deletion(7), n = 63 (A) . | Deletion(7q), n = 72 (B) . | UPD(7q), n = 26 (C) . | P (only significant comparisons reported) . |
|---|---|---|---|---|
| Median age, y (range) | 58 (27-70) | 64 (56-72) | 68 (63.2-77) | A vs B (P = .01) A vs C (P = .009) |
| Sex | ||||
| Male, % | 59 | 56 | 57 | |
| Female, % | 41 | 44 | 43 | |
| White blood cell count, × 109/L, median (IQR) | 5.5 (2.7-25.7) | 4.3 (2.1-13.5) | 10.5 (8.1-37.9) | C vs A (P = .028) C vs B (P = .01) |
| Hemoglobin, g/dL, mean ± SD | 9.1 ± 1.9 | 9.2 (8.9-10) | 9.1 ± 2.1 | |
| Mean corpuscular volume, median (IQR) | 91 (85-99) | 90 (86-104.8) | 90 (85-103) | |
| Platelets, × 109/L, median (IQR) | 47 (22-71) | 50 (24-86) | 46 (20.2-146.2) | |
| BM cellularity, median (%) | 35 (22-61) | 75 (45-90) | 76(55-100) | A vs B (P = .03) A vs C (P = .036) |
IQR indicates interquartile range; BM, bone marrow; UPD, uniparental disomy; and CMML, chronic myeloid leukemia..