Relationship between hematologic response and changes in cardiac parameters
| . | Patients with a hematologic complete response (N = 56) . | Patients with a hematologic response (≥ = PR) (N = 124) . | Patients with no hematologic response (N = 33) P . | |||
|---|---|---|---|---|---|---|
| Parameter, N (%) | ||||||
| Conventional cardiac response | 55 | 33 (60) | 122 | 57 (47) | 32 | 5 (16) |
| NT-Pro BNP decrease ≥ 30% | 25 | 21 (84) | 65 | 51 (78) | 19 | 7 (37) |
| Parameter, N, Change from baseline: median (IQR) | ||||||
| Septal thickness, mm | 55 | −2 (−3 to +1) | 122 | −1 (−3 to +0) | 32 | 0 (−1 to +1) |
| Ejection fraction, % | 56 | +4 (−10 to +1) | 124 | +2 (+7 to −2) | 33 | 0 (−4 to +4) |
| LV mass index | 54 | −8 (−36 to +2) | 120 | −11 (−32 to +2) | 32 | 0 (−13 to +15) |
| Troponin T, μg/mL | 42 | −0.01 (−0.04 to +0.01) | 92 | −0.01 (−0.01 to +0.03) | 20 | 0 (−0.01 to +0.01) |
| NT-Pro BNP, pg/mL | 25 | −963 (−1470 to +91) | 65 | −745 (−1979 to +80) | 19 | 0 (−262 to + 1269) |
| . | Patients with a hematologic complete response (N = 56) . | Patients with a hematologic response (≥ = PR) (N = 124) . | Patients with no hematologic response (N = 33) P . | |||
|---|---|---|---|---|---|---|
| Parameter, N (%) | ||||||
| Conventional cardiac response | 55 | 33 (60) | 122 | 57 (47) | 32 | 5 (16) |
| NT-Pro BNP decrease ≥ 30% | 25 | 21 (84) | 65 | 51 (78) | 19 | 7 (37) |
| Parameter, N, Change from baseline: median (IQR) | ||||||
| Septal thickness, mm | 55 | −2 (−3 to +1) | 122 | −1 (−3 to +0) | 32 | 0 (−1 to +1) |
| Ejection fraction, % | 56 | +4 (−10 to +1) | 124 | +2 (+7 to −2) | 33 | 0 (−4 to +4) |
| LV mass index | 54 | −8 (−36 to +2) | 120 | −11 (−32 to +2) | 32 | 0 (−13 to +15) |
| Troponin T, μg/mL | 42 | −0.01 (−0.04 to +0.01) | 92 | −0.01 (−0.01 to +0.03) | 20 | 0 (−0.01 to +0.01) |
| NT-Pro BNP, pg/mL | 25 | −963 (−1470 to +91) | 65 | −745 (−1979 to +80) | 19 | 0 (−262 to + 1269) |
NT-Pro BNP indicates N-terminal-pro brain natriuretic peptide; and LV, left ventricle.