Table 3

FY2010 Extramural NHLBI projects (including all mechanisms) by RCDC topics that relate to specific disease categories

RCDC topicNonclinical projects
Clinical projects
No.Total funding (% extramural funding)Median cost per project (25th, 75th percentiles)No.Total funding (% extramural funding)Median cost per project (25th and 75th percentiles)
Cardiovascular 1913 865 499 (35%) 374 (270, 414) 1005 539 545 (22%) 379 (142, 658) 
Atherosclerosis 393 243 991 (10%) 375 (303, 414) 271 160 713 (7%) 401 (198, 722) 
CAD 440 221 791 (9%) 380 (323, 420) 267 156 696 (6%) 422 (200, 721) 
Heart disease 1258 595 073 (24%) 375 (286, 417) 727 410 409 (17%) 386 (147, 685) 
Hypertension 231 105 746 (4%) 370 (312, 401) 111 50 652 (2%) 371 (151, 594) 
Lung 697 325 329 (13%) 376 (293, 410) 605 283 649 (12%) 375 (137, 610) 
COPD 55 58 142 (2%) 410 (346, 1730) 84 44 767 (2%) 372 (142, 703) 
Asthma 94 40 732 (2%) 373 (249, 400) 144 79 092 (3%) 407 (160, 750) 
ARDS 110 61 255 (3%) 384 (335, 410) 82 29 665 (1%) 326 (135, 415) 
Cystic fibrosis 42 21 253 (1%) 371 (326, 475) 37 17 928 (1%) 385 (173, 648) 
Sleep 55 16 969 (1%) 367 (230, 393) 97 51 527 (2%) 405 (189, 607) 
Hematology 406 165 228 (7%) 370 (191, 410) 295 139 989 (6%) 375 (140, 464) 
Sickle cell 21 9325 (< 1%) 338 (139, 458) 60 28 774 (1%) 303 (125, 451) 
Cooley anemia 4949 (< 1%) 394 (373, 429) 8112 (< 1%) 411 (390, 1327) 
RCDC topicNonclinical projects
Clinical projects
No.Total funding (% extramural funding)Median cost per project (25th, 75th percentiles)No.Total funding (% extramural funding)Median cost per project (25th and 75th percentiles)
Cardiovascular 1913 865 499 (35%) 374 (270, 414) 1005 539 545 (22%) 379 (142, 658) 
Atherosclerosis 393 243 991 (10%) 375 (303, 414) 271 160 713 (7%) 401 (198, 722) 
CAD 440 221 791 (9%) 380 (323, 420) 267 156 696 (6%) 422 (200, 721) 
Heart disease 1258 595 073 (24%) 375 (286, 417) 727 410 409 (17%) 386 (147, 685) 
Hypertension 231 105 746 (4%) 370 (312, 401) 111 50 652 (2%) 371 (151, 594) 
Lung 697 325 329 (13%) 376 (293, 410) 605 283 649 (12%) 375 (137, 610) 
COPD 55 58 142 (2%) 410 (346, 1730) 84 44 767 (2%) 372 (142, 703) 
Asthma 94 40 732 (2%) 373 (249, 400) 144 79 092 (3%) 407 (160, 750) 
ARDS 110 61 255 (3%) 384 (335, 410) 82 29 665 (1%) 326 (135, 415) 
Cystic fibrosis 42 21 253 (1%) 371 (326, 475) 37 17 928 (1%) 385 (173, 648) 
Sleep 55 16 969 (1%) 367 (230, 393) 97 51 527 (2%) 405 (189, 607) 
Hematology 406 165 228 (7%) 370 (191, 410) 295 139 989 (6%) 375 (140, 464) 
Sickle cell 21 9325 (< 1%) 338 (139, 458) 60 28 774 (1%) 303 (125, 451) 
Cooley anemia 4949 (< 1%) 394 (373, 429) 8112 (< 1%) 411 (390, 1327) 

All costs are in units of $1000. All data were obtained from the NIH Research Portfolio Online Reporting Tools (RePORT). Estimates of funding for various RCDCs are at http://report.nih.gov/categorical_spending.aspx. RCDC topics are not necessarily exclusive of one another (hence, total percentages exceed 100). Clinical projects are those categorized in RCDC as “Clinical Research” or “Clinical Trials.” Total NHLBI extramural funding in FY10 was $2 441 772 050. Numbers of projects, total funding in each RCDC area, and median (25th, 75th percentiles) costs per project were calculated using the SAS Version 9.2 “Proc Tabulate” procedure.

CAD indicates coronary artery disease; COPD, chronic obstructive pulmonary disease; and ARDS, acute respiratory distress syndrome.

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