Patient characteristics and response to decitabine treatment
Patient no. . | Age, y . | Sex . | Gene mutation . | Eventual clinical outcome . | ||||||
---|---|---|---|---|---|---|---|---|---|---|
NPM1 . | FLT3-ITD . | CEBPA . | DNMT3A . | TET2 . | IDH1 . | IDH2 . | ||||
1 | 73 | F | MUT | WT | WT | WT | MUT | WT | WT | Non-CR |
3 | 69 | F | MUT | WT | WT | MUT | WT | WT | WT | CR |
4 | 80 | M | WT | WT | WT | WT | WT | WT | WT | Non-CR |
5 | 85 | M | WT | WT | WT | WT | WT | MUT | WT | CR |
6 | 71 | M | WT | WT | WT | WT | WT | WT | WT | Non-CR |
7 | 84 | F | WT | WT | WT | WT | WT | WT | WT | Non-CR |
8 | 66 | F | WT | WT | WT | WT | WT | WT | WT | CR |
14 | 80 | F | WT | WT | WT | ND | ND | WT | WT | CR |
15 | 75 | F | WT | WT | WT | WT | WT | WT | WT | CR |
17 | 74 | F | WT | WT | WT | WT | WT | WT | MUT | CR |
18 | 74 | M | MUT | WT | WT | WT | WT | WT | WT | CR |
19 | 73 | F | WT | WT | WT | WT | WT | MUT | WT | Non-CR |
20 | 81 | M | WT | WT | WT | WT | MUT | WT | WT | CR |
21 | 76 | M | WT | WT | WT | WT | WT | WT | WT | Non-CR |
23 | 67 | M | WT | WT | WT | WT | WT | WT | WT | Non-CR |
24 | 68 | M | MUT | WT | WT | MUT | WT | WT | WT | CR |
Patient no. . | Age, y . | Sex . | Gene mutation . | Eventual clinical outcome . | ||||||
---|---|---|---|---|---|---|---|---|---|---|
NPM1 . | FLT3-ITD . | CEBPA . | DNMT3A . | TET2 . | IDH1 . | IDH2 . | ||||
1 | 73 | F | MUT | WT | WT | WT | MUT | WT | WT | Non-CR |
3 | 69 | F | MUT | WT | WT | MUT | WT | WT | WT | CR |
4 | 80 | M | WT | WT | WT | WT | WT | WT | WT | Non-CR |
5 | 85 | M | WT | WT | WT | WT | WT | MUT | WT | CR |
6 | 71 | M | WT | WT | WT | WT | WT | WT | WT | Non-CR |
7 | 84 | F | WT | WT | WT | WT | WT | WT | WT | Non-CR |
8 | 66 | F | WT | WT | WT | WT | WT | WT | WT | CR |
14 | 80 | F | WT | WT | WT | ND | ND | WT | WT | CR |
15 | 75 | F | WT | WT | WT | WT | WT | WT | WT | CR |
17 | 74 | F | WT | WT | WT | WT | WT | WT | MUT | CR |
18 | 74 | M | MUT | WT | WT | WT | WT | WT | WT | CR |
19 | 73 | F | WT | WT | WT | WT | WT | MUT | WT | Non-CR |
20 | 81 | M | WT | WT | WT | WT | MUT | WT | WT | CR |
21 | 76 | M | WT | WT | WT | WT | WT | WT | WT | Non-CR |
23 | 67 | M | WT | WT | WT | WT | WT | WT | WT | Non-CR |
24 | 68 | M | MUT | WT | WT | MUT | WT | WT | WT | CR |
FLT3-ITD indicates internal tandem duplication of the FLT3 gene; CR, complete remission (no disease and full blood count recovery); and Non-CR, noncomplete remission.