Table 1 Clinical data for patients with... | American Society of Hematology

Table 1

Clinical data for patients with CLL

Characteristic	13q normal (n = 25)*	del(13q14) (n = 27)
Male/female sex, n	16/9	21/6
Median time from diagnosis to sample collection, mo	36	66
FISH cytogenetics, n*
Cytogenetically normal	13	0
11q−	1	7
17p−	2	8
Trisomy 12	6	4
ZAP70 expression, n
≤ 20%	2	11
> 20%	23	17
Ig heavy-chain variable region status, n†
Unmutated (> 98% homology)	20	18
Mutated (< 98% homology)	5	10
Therapy began after collection
No	5	4
Yes	21	24

Characteristic	13q normal (n = 25)*	del(13q14) (n = 27)
Male/female sex, n	16/9	21/6
Median time from diagnosis to sample collection, mo	36	66
FISH cytogenetics, n*
Cytogenetically normal	13	0
11q−	1	7
17p−	2	8
Trisomy 12	6	4
ZAP70 expression, n
≤ 20%	2	11
> 20%	23	17
Ig heavy-chain variable region status, n†
Unmutated (> 98% homology)	20	18
Mutated (< 98% homology)	5	10
Therapy began after collection
No	5	4
Yes	21	24

FISH karyotype was known for 50 patients and was not done for 3 who were included under the 13q normal column.

Ig heavy-chain variable region status was known for 50 patients.