Multivariate analysis for pOS, pEFS, and pDFS
| . | HR . | 95% CI . | P . | |
|---|---|---|---|---|
| Lower . | Upper . | |||
| pOS | ||||
| High GATA2 expression | 1.724 | 1.012 | 2.938 | .045 |
| Age | 1.031 | 0.982 | 1.083 | .219 |
| WBC count | 1.003 | 1.001 | 1.006 | .008 |
| FLT3-ITD | 0.924 | 0.502 | 1.700 | .799 |
| NPM1 mutation | 0.169 | 0.040 | 0.714 | .016 |
| Favorable karyotype | 0.145 | 0.069 | 0.306 | < .001 |
| CEBPA double mutation | 0.128 | 0.017 | 0.949 | .044 |
| pEFS | ||||
| High GATA2 expression | 2.050 | 1.312 | 3.204 | .002 |
| Age | 1.058 | 1.014 | 1.104 | .010 |
| WBC count | 1.002 | 0.999 | 1.004 | .189 |
| FLT3-ITD | 0.791 | 0.467 | 1.342 | .385 |
| Favorable karyotype | 0.204 | 0.121 | 0.345 | < .001 |
| CEBPA double mutation | 0.181 | 0.054 | 0.601 | .005 |
| NPM1 mutation | 0.130 | 0.039 | 0.426 | .001 |
| pDFS | ||||
| High GATA2 expression | 2.290 | 1.300 | 4.034 | .004 |
| Age | 1.073 | 1.016 | 1.133 | .011 |
| WBC count | 1.000 | 0.997 | 1.004 | .960 |
| FLT3-ITD | 0.874 | 0.456 | 1.677 | .687 |
| Favorable karyotype | 0.160 | 0.083 | 0.307 | < .001 |
| NPM1 mutation | 0.140 | 0.041 | 0.471 | .002 |
| CEBPA double mutation | 0.134 | 0.030 | 0.588 | .008 |
| . | HR . | 95% CI . | P . | |
|---|---|---|---|---|
| Lower . | Upper . | |||
| pOS | ||||
| High GATA2 expression | 1.724 | 1.012 | 2.938 | .045 |
| Age | 1.031 | 0.982 | 1.083 | .219 |
| WBC count | 1.003 | 1.001 | 1.006 | .008 |
| FLT3-ITD | 0.924 | 0.502 | 1.700 | .799 |
| NPM1 mutation | 0.169 | 0.040 | 0.714 | .016 |
| Favorable karyotype | 0.145 | 0.069 | 0.306 | < .001 |
| CEBPA double mutation | 0.128 | 0.017 | 0.949 | .044 |
| pEFS | ||||
| High GATA2 expression | 2.050 | 1.312 | 3.204 | .002 |
| Age | 1.058 | 1.014 | 1.104 | .010 |
| WBC count | 1.002 | 0.999 | 1.004 | .189 |
| FLT3-ITD | 0.791 | 0.467 | 1.342 | .385 |
| Favorable karyotype | 0.204 | 0.121 | 0.345 | < .001 |
| CEBPA double mutation | 0.181 | 0.054 | 0.601 | .005 |
| NPM1 mutation | 0.130 | 0.039 | 0.426 | .001 |
| pDFS | ||||
| High GATA2 expression | 2.290 | 1.300 | 4.034 | .004 |
| Age | 1.073 | 1.016 | 1.133 | .011 |
| WBC count | 1.000 | 0.997 | 1.004 | .960 |
| FLT3-ITD | 0.874 | 0.456 | 1.677 | .687 |
| Favorable karyotype | 0.160 | 0.083 | 0.307 | < .001 |
| NPM1 mutation | 0.140 | 0.041 | 0.471 | .002 |
| CEBPA double mutation | 0.134 | 0.030 | 0.588 | .008 |
Multivariate Cox regression model for pOS, pEFS, and pDFS. Age and WBC count are analyzed as continuous variables. GATA2 expression is dichotomized. P values in bold indicate whether differences are significant at the level of .05.
95% CI indicates 95% confidence interval.