Summary of genetic aberration associations
Overall associations |
At diagnosis |
FLT3-ITD+ with S-isoform, pWBChigh |
FLT3-D835+ with pWBChigh |
FLT3-ITD+ and FLT3-D835+ negatively |
At relapse |
FLT3-ITD+ with S-isoform, pWBChigh, ACA negatively |
ACA with FLT3-ITD+ negatively, L-isoform, postrelapse death |
PRα/LBD+ with pWBClow |
ATRA treatment stratified associations at relapse |
Relapse On-ATRA |
FLT3-ITD+ with S-isoform, PRα/LBD+ |
Relapse Off-ATRA |
FLT3-ITD+ with S-isoform, pWBChigh, ACA and PRα/LBD+ negatively |
ACA with pWBClow, L-isoform, FLT3-ITD+ negatively |
PRα/LBD+ with pWBClow, ACA, FLT3-ITD+ negatively |
Overall associations |
At diagnosis |
FLT3-ITD+ with S-isoform, pWBChigh |
FLT3-D835+ with pWBChigh |
FLT3-ITD+ and FLT3-D835+ negatively |
At relapse |
FLT3-ITD+ with S-isoform, pWBChigh, ACA negatively |
ACA with FLT3-ITD+ negatively, L-isoform, postrelapse death |
PRα/LBD+ with pWBClow |
ATRA treatment stratified associations at relapse |
Relapse On-ATRA |
FLT3-ITD+ with S-isoform, PRα/LBD+ |
Relapse Off-ATRA |
FLT3-ITD+ with S-isoform, pWBChigh, ACA and PRα/LBD+ negatively |
ACA with pWBClow, L-isoform, FLT3-ITD+ negatively |
PRα/LBD+ with pWBClow, ACA, FLT3-ITD+ negatively |