Table 2 Unadjusted clinical outcomes by... | American Society of Hematology

Table 2

Unadjusted clinical outcomes by degree of HLA-A, -B, -C, -DRB1 matching

	N	% (95% CI)	P
Survival at 5 y			.003
8/8 match	372	65 (60-70)	*
1 MM	191	57 (50-64)	.07
2 MM	100	46 (37-56)	.001
Acute GVHD II-IV at 100 d			.82
8/8 match	384	42 (37-47)	*
1 MM	190	40 (33-47)	.63
2 MM	89	44 (34-55)	.77
Acute GVHD III-IV at 100 d			.59
8/8 match	384	23 (19-28)	*
1 MM	190	26 (20-32)	.58
2 MM	89	29 (20-39)	.33
Chronic GVHD at 1 y			.62
8/8 match	384	28 (23-33)	*
1 MM	190	24 (18-31)	.37
2 MM	89	29 (19-40)	.89
Graft failure at 1 y			< .0001
8/8 match	386	11 (8-14)	*
1 MM	188	28 (21-34)	< .0001
2 MM	89	24 (16-33)	.008

	N	% (95% CI)	P
Survival at 5 y			.003
8/8 match	372	65 (60-70)	*
1 MM	191	57 (50-64)	.07
2 MM	100	46 (37-56)	.001
Acute GVHD II-IV at 100 d			.82
8/8 match	384	42 (37-47)	*
1 MM	190	40 (33-47)	.63
2 MM	89	44 (34-55)	.77
Acute GVHD III-IV at 100 d			.59
8/8 match	384	23 (19-28)	*
1 MM	190	26 (20-32)	.58
2 MM	89	29 (20-39)	.33
Chronic GVHD at 1 y			.62
8/8 match	384	28 (23-33)	*
1 MM	190	24 (18-31)	.37
2 MM	89	29 (19-40)	.89
Graft failure at 1 y			< .0001
8/8 match	386	11 (8-14)	*
1 MM	188	28 (21-34)	< .0001
2 MM	89	24 (16-33)	.008

N indicates the number of patient-donor pairs; CI, confidence interval; MM, mismatch; and GVHD, graft-versus-host disease.

Baseline.