Defective nuclear localization of Hsp70 correlates with MDS dyserythropoiesis
| . | MDS with dyserythropoiesis . | MDS without dyserythropoiesis . | Controls . | χ2 test . |
|---|---|---|---|---|
| Nuclear Hsp70 | 11 | 9 | 18 | P < .0001 |
| Cytosolic Hsp70 | 30 | 1 | 2 |
| . | MDS with dyserythropoiesis . | MDS without dyserythropoiesis . | Controls . | χ2 test . |
|---|---|---|---|---|
| Nuclear Hsp70 | 11 | 9 | 18 | P < .0001 |
| Cytosolic Hsp70 | 30 | 1 | 2 |
MDS erythroblast samples with (n = 41) or without (n = 10) dyserythropoiesis and 20 were tested for Hsp70 subcellular localization by immunofluorescence or immunoblot. χ2 test for statistical analysis.
MDS indicates myelodysplastic syndrome.