Baseline status and clinical course of patients achieving major cytogenetic response
| Patient . | Baseline hematologic/cytogenetic status . | Disposition . | No. of cycles received . | Best cytogenetic response on study . |
|---|---|---|---|---|
| 001-009 | CHR−/100% Ph+ | Ongoing | 14 | CCyR |
| 001-012 | CHR+/95% Ph+ | Ongoing | 17 | PCyR |
| 005-001 | CHR+/20% Ph+ | Ongoing | 32 | CCyR |
| 005-002 | CHR+/45% Ph+ | Ongoing | 5 | CCyR |
| 009-002 | CHR+/Not done | Ongoing | 21 | CCyR |
| 010-001 | CHR+/30% Ph+ | Ongoing | 16 | CCyR |
| 020-005 | CHR+/90% Ph+ | Ongoing | 15 | CCyR |
| 021-004 | CHR+/100% Ph+ | Discontinued (to receive allograft) | 3 | PCyR |
| 023-003 | CHR+/74% Ph+ | Discontinued (to receive cord blood transplant) | 10 | CCyR |
| 028-001 | CHR−/100% Ph+ | Discontinued (failure to achieve meaningful response) | 11 | PCyR |
| 028-002 | CHR−/91% Ph+ | Discontinued (failure to achieve meaningful response) | 9 | CCyR |
| 071-002 | CHR−/100% Ph+ | Discontinued (disease progression) | 10 | PCyR |
| 071-003 | CHR−/40% Ph+ | Discontinued (adverse event) | 5 | CCyR |
| 090-002 | CHR+/13% Ph+ | Discontinued (withdrawal by request) | 3 | CCyR |
| Patient . | Baseline hematologic/cytogenetic status . | Disposition . | No. of cycles received . | Best cytogenetic response on study . |
|---|---|---|---|---|
| 001-009 | CHR−/100% Ph+ | Ongoing | 14 | CCyR |
| 001-012 | CHR+/95% Ph+ | Ongoing | 17 | PCyR |
| 005-001 | CHR+/20% Ph+ | Ongoing | 32 | CCyR |
| 005-002 | CHR+/45% Ph+ | Ongoing | 5 | CCyR |
| 009-002 | CHR+/Not done | Ongoing | 21 | CCyR |
| 010-001 | CHR+/30% Ph+ | Ongoing | 16 | CCyR |
| 020-005 | CHR+/90% Ph+ | Ongoing | 15 | CCyR |
| 021-004 | CHR+/100% Ph+ | Discontinued (to receive allograft) | 3 | PCyR |
| 023-003 | CHR+/74% Ph+ | Discontinued (to receive cord blood transplant) | 10 | CCyR |
| 028-001 | CHR−/100% Ph+ | Discontinued (failure to achieve meaningful response) | 11 | PCyR |
| 028-002 | CHR−/91% Ph+ | Discontinued (failure to achieve meaningful response) | 9 | CCyR |
| 071-002 | CHR−/100% Ph+ | Discontinued (disease progression) | 10 | PCyR |
| 071-003 | CHR−/40% Ph+ | Discontinued (adverse event) | 5 | CCyR |
| 090-002 | CHR+/13% Ph+ | Discontinued (withdrawal by request) | 3 | CCyR |
CHR indicates complete hematologic response; CCyR, complete cytogenetic response; and PCyR, partial cytogenetic response.