Study design and dosing schedule
| Group . | N . | Doses and administration schedule . | ||
|---|---|---|---|---|
| 3H9, 0.6 mg/kg IV . | Vehicle, SC daily . | ALX-0681, 2.5 mg/kg SC daily . | ||
| Control animals | 4 | d 1, 3, 5, 7, 9 | d 1-11 | |
| Preventive ALX-0681–treated animals | 4 | d 1 and 3 | d 1-5 | |
| Therapeutic ALX-0681–treated animals | 4 | d 1, 3, 5, 7, 9 | d 1-4 | d 5-11 |
| Group . | N . | Doses and administration schedule . | ||
|---|---|---|---|---|
| 3H9, 0.6 mg/kg IV . | Vehicle, SC daily . | ALX-0681, 2.5 mg/kg SC daily . | ||
| Control animals | 4 | d 1, 3, 5, 7, 9 | d 1-11 | |
| Preventive ALX-0681–treated animals | 4 | d 1 and 3 | d 1-5 | |
| Therapeutic ALX-0681–treated animals | 4 | d 1, 3, 5, 7, 9 | d 1-4 | d 5-11 |
Table shows an overview of the timing of injections in the different study groups.