Table 2

Details of SRA seroconversion in 13 heparin reexposures performed for cardiac or vascular surgery

PatientSerotonin-release (%) at concentrations of UFHPlatelet count decrease >30% or thrombosis on or after POD5
00.10.3100
37 59 83 50 No 
17 84 No 
10 11 73 No 
11 75 89 No 
14 50 100 17 No 
15 54 89 96 24 No 
16 47 88 No 
17 95 100 98 HIT: 86% platelet decrease from 148 to 20 beginning on POD7 (Figure 4) 
22 4 (79*82 89 No; however, atrial fibrillation developed on POD14, and in vitro cross-reactivity (79% serotonin release) with danaparoid 0.3 anti-Xa U/mL was shown (Figure 4) 
PatientSerotonin-release (%) at concentrations of UFHPlatelet count decrease >30% or thrombosis on or after POD5
00.10.3100
37 59 83 50 No 
17 84 No 
10 11 73 No 
11 75 89 No 
14 50 100 17 No 
15 54 89 96 24 No 
16 47 88 No 
17 95 100 98 HIT: 86% platelet decrease from 148 to 20 beginning on POD7 (Figure 4) 
22 4 (79*82 89 No; however, atrial fibrillation developed on POD14, and in vitro cross-reactivity (79% serotonin release) with danaparoid 0.3 anti-Xa U/mL was shown (Figure 4) 
*

In vitro cross-reactivity (79% serotonin release) with danaparoid 0.3 anti-Xa U/mL was demonstrated (Figure 2).

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