MCV, HbF, D50, and %DRBCs by α-thalassemia status
| α-thalassemia status . | No. . | MCV, mean ± SD . | HbF, mean ± SD . | D50, mean ± SD . | %DRBCs, mean ± SD . |
|---|---|---|---|---|---|
| Normal | 216 | 92.6 ± 8.6*† | 8.4 ± 5.7* | 1.096 ± 0.003* | 14.6 ± 7.7* |
| 1-gene deletion | 183 | 84.6 ± 6.8*‡ | 6.8 ± 4.7* | 1.095 ± 0.003* | 12.5 ± 7.3* |
| 2-gene deletions | 46 | 71.1 ± 4.4†‡ | 4.4 ± 3.7* | 1.092 ± 0.003*† | 4.5 ± 4.3*† |
| Gene triplication | 7 | 92.4 ± 7.9‡ | 7.8 ± 4.8 | 1.098 ± 0.002† | 16.9 ± 4.8† |
| α-thalassemia status . | No. . | MCV, mean ± SD . | HbF, mean ± SD . | D50, mean ± SD . | %DRBCs, mean ± SD . |
|---|---|---|---|---|---|
| Normal | 216 | 92.6 ± 8.6*† | 8.4 ± 5.7* | 1.096 ± 0.003* | 14.6 ± 7.7* |
| 1-gene deletion | 183 | 84.6 ± 6.8*‡ | 6.8 ± 4.7* | 1.095 ± 0.003* | 12.5 ± 7.3* |
| 2-gene deletions | 46 | 71.1 ± 4.4†‡ | 4.4 ± 3.7* | 1.092 ± 0.003*† | 4.5 ± 4.3*† |
| Gene triplication | 7 | 92.4 ± 7.9‡ | 7.8 ± 4.8 | 1.098 ± 0.002† | 16.9 ± 4.8† |
The symbols indicate significant differences between the means sharing the same symbol. For example, the mean MCV for SS patients with normal α-thalassemia status differed significantly from that of patients with 1- or 2-gene deletions. The statistical significance, defined as P < .05, was pairwise comparisons using the Tukey adjustment.