Pathologic classification of diseases with tissue deposition or precipitation of monoclonal Ig
| Organized . | Nonorganized (granular) . | |||
|---|---|---|---|---|
| Crystals . | Fibrillar . | Microtubular . | MIDD (Randall type) . | Other . |
| Myeloma cast nephropathy | Light chain amyloidosis | Type I and type II cryoglobulinemic glomerulonephritis | LCDD | Proliferative GN with monoclonal Ig deposits |
| Light chain proximal tubulopathy (with or without Fanconi syndrome) | Nonamyloid | Immunotactoid GN | LHCDD | Waldenström |
| Crystal-storing histocytosis | Fibrillary GN* | GOMMID | HCDD | Macroglobulinemia |
| Organized . | Nonorganized (granular) . | |||
|---|---|---|---|---|
| Crystals . | Fibrillar . | Microtubular . | MIDD (Randall type) . | Other . |
| Myeloma cast nephropathy | Light chain amyloidosis | Type I and type II cryoglobulinemic glomerulonephritis | LCDD | Proliferative GN with monoclonal Ig deposits |
| Light chain proximal tubulopathy (with or without Fanconi syndrome) | Nonamyloid | Immunotactoid GN | LHCDD | Waldenström |
| Crystal-storing histocytosis | Fibrillary GN* | GOMMID | HCDD | Macroglobulinemia |
GN indicates glomerulonephritis; GOMMID, glomerulonephritis with organized microtubular monoclonal Ig deposits; LCDD, light-chain deposition disease; LHCDD, light- and heavy-chain deposition disease; and HCDD, heavy-chain deposition disease.
Mostly associated with polyclonal IgG deposits.