Crystallographic statistics
| . | KTP-185-ScXPO1(T539C)-HsRan-ScRanBP1 . |
|---|---|
| Cell axial lengths (Å) | a = b = 106.45, c = 306.80 |
| Spacegroup | P43212 |
| Data collection | |
| Resolution range (Å) | 50.00-2.10 (2.14-2.10) |
| No. of observed reflections | 665019 (25 175) |
| No. of unique reflections | 100063 (4750) |
| Completeness (%) | 96.0 (92.8) |
| Redundancy | 6.7 (5.3) |
| aRsym (%) | 6.8 (47.8) |
| Mean I/Iσ | 29.1 (1.9) |
| Refinement | |
| Resolution range (Å) | 50.00-2.10 (2.15–2.10) |
| No. of working reflections | 89 096 (6208) |
| No. of test reflections | 5004 (326) |
| bRwork | 0.151 (0.248) |
| cRfree | 0.192 (0.288) |
| R.m.s. deviation bond lengths (Å) | 0.014 |
| R.m.s. deviation bond angles (°) | 1.51 |
| Average B-factors (Å2) | Protein: 27.1 |
| KPT-185: 34.2 | |
| Solvent content (%) | 57.6 |
| Ramachandran plot | |
| Most favored (%) | 94.1 |
| Allowed (%) | 5.6 |
| General allowed (%) | 0.2 |
| Disallowed (%) | 0.1 |
| . | KTP-185-ScXPO1(T539C)-HsRan-ScRanBP1 . |
|---|---|
| Cell axial lengths (Å) | a = b = 106.45, c = 306.80 |
| Spacegroup | P43212 |
| Data collection | |
| Resolution range (Å) | 50.00-2.10 (2.14-2.10) |
| No. of observed reflections | 665019 (25 175) |
| No. of unique reflections | 100063 (4750) |
| Completeness (%) | 96.0 (92.8) |
| Redundancy | 6.7 (5.3) |
| aRsym (%) | 6.8 (47.8) |
| Mean I/Iσ | 29.1 (1.9) |
| Refinement | |
| Resolution range (Å) | 50.00-2.10 (2.15–2.10) |
| No. of working reflections | 89 096 (6208) |
| No. of test reflections | 5004 (326) |
| bRwork | 0.151 (0.248) |
| cRfree | 0.192 (0.288) |
| R.m.s. deviation bond lengths (Å) | 0.014 |
| R.m.s. deviation bond angles (°) | 1.51 |
| Average B-factors (Å2) | Protein: 27.1 |
| KPT-185: 34.2 | |
| Solvent content (%) | 57.6 |
| Ramachandran plot | |
| Most favored (%) | 94.1 |
| Allowed (%) | 5.6 |
| General allowed (%) | 0.2 |
| Disallowed (%) | 0.1 |