Table 2

CD30 expression in various T-cell subsets in patients after allogenic HCT

T-cell subsetGVHDNONEP
All CD4 3.1 (0.1-21.3) 1.4 (0.4-10.3) .100 
    Naïve CD4 0.2 (0.0-3.4) 0.2 (0.0-16.7) .348 
    Central memory CD4 5.0 (0.1-41.0) 2.4 (0.9-23.3) .054 
    Effector memory CD4 2.6 (0.3-10.9) 1.7 (0.6-5.8) .482 
    Regulatory T cells 10.1 (2.4-27.6) 6.2 (0.0-20.8) .155 
All CD8 2.3 (0.3-18.2) 0.6 (0.2-3.2) < .001 
    Naïve CD8 0.5 (0.0-16.2) 0.3 (0.0-2.9) .500 
    Central memory CD8 12.4 (0.8-33.4) 2.1 (0.7-17.5) < .001 
    Effector memory CD8 2.4 (0.7-10.8) 0.8 (0.3-2.9) < .001 
T-cell subsetGVHDNONEP
All CD4 3.1 (0.1-21.3) 1.4 (0.4-10.3) .100 
    Naïve CD4 0.2 (0.0-3.4) 0.2 (0.0-16.7) .348 
    Central memory CD4 5.0 (0.1-41.0) 2.4 (0.9-23.3) .054 
    Effector memory CD4 2.6 (0.3-10.9) 1.7 (0.6-5.8) .482 
    Regulatory T cells 10.1 (2.4-27.6) 6.2 (0.0-20.8) .155 
All CD8 2.3 (0.3-18.2) 0.6 (0.2-3.2) < .001 
    Naïve CD8 0.5 (0.0-16.2) 0.3 (0.0-2.9) .500 
    Central memory CD8 12.4 (0.8-33.4) 2.1 (0.7-17.5) < .001 
    Effector memory CD8 2.4 (0.7-10.8) 0.8 (0.3-2.9) < .001 

Subsets were defined phenotypically as discussed in “Flow Cytometry.” Values for GVHD and NONE groups are given as the percentage of cells in each subset expressing CD30. Range of values is given in parentheses.

HCT indicates hematopoietic cell transplantation.

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