Frequency of clonal subpopulations carrying a mutation
| Sample . | Translocation group . | Gene . | SNV . | Copy no. . | Frequency of SNV, % . | Estimated % of tumor population* . | Major or minor clone component . |
|---|---|---|---|---|---|---|---|
| 142 | t(4;14) | KRAS | c.A182G | 2 | 36 | 72 | Major |
| 738 | t(4;14) | KRAS | c.G436C | 2 | 36 | 72 | Major |
| 879 | t(11;14) | KRAS | c.A199C | 2 | 35 | 70 | Major |
| 879 | t(11;14) | KRAS | c.A183C | 2 | 34 | 68 | Major |
| 245 | t(4;14) | KRAS | c.G38A | 2 | 33 | 66 | Major |
| 3 | t(11;14) | KRAS | c.A182G | 2 | 10 | 20 | Minor |
| 3 | t(11;14) | KRAS | c.G34C | 2 | 24 | 48 | Minor |
| 827 | t(11;14) | KRAS | c.A182G | 2 | 14 | 28 | Minor |
| 1112 | t(11;14) | KRAS | c.G38A | 2 | 14 | 28 | Minor |
| 983 | t(11;14) | NRAS | c.C181A | 2 | 47 | 94 | Major |
| 203 | t(11;14) | NRAS | c.C181A | 2 | 48 | 96 | Major |
| 482 | t(11;14) | NRAS | c.A182G | 2 | 16 | 32 | Minor |
| 1890 | t(4;14) | NRAS | c.A182G | 2 | 17 | 34 | Minor |
| 468 | t(11;14) | BRAF | c.T1799A | 2 | 46 | 92 | Major |
| 405 | t(4;14) | BRAF | c.T1799A | 3 | 12 | 36 | Minor |
| 983 | t(11;14) | DIS3 | c.G2249A | 2 | 46 | 92 | Major |
| 738 | t(4;14) | DIS3 | c.A1030C | 1 | 81 | 81 | Major |
| 468 | t(11;14) | DIS3 | c.A2765C | 1 | 69 | 69 | Major |
| 405 | t(4;14) | DIS3 | c.T1501G | 1 | 29 | 29 | Minor |
| Sample . | Translocation group . | Gene . | SNV . | Copy no. . | Frequency of SNV, % . | Estimated % of tumor population* . | Major or minor clone component . |
|---|---|---|---|---|---|---|---|
| 142 | t(4;14) | KRAS | c.A182G | 2 | 36 | 72 | Major |
| 738 | t(4;14) | KRAS | c.G436C | 2 | 36 | 72 | Major |
| 879 | t(11;14) | KRAS | c.A199C | 2 | 35 | 70 | Major |
| 879 | t(11;14) | KRAS | c.A183C | 2 | 34 | 68 | Major |
| 245 | t(4;14) | KRAS | c.G38A | 2 | 33 | 66 | Major |
| 3 | t(11;14) | KRAS | c.A182G | 2 | 10 | 20 | Minor |
| 3 | t(11;14) | KRAS | c.G34C | 2 | 24 | 48 | Minor |
| 827 | t(11;14) | KRAS | c.A182G | 2 | 14 | 28 | Minor |
| 1112 | t(11;14) | KRAS | c.G38A | 2 | 14 | 28 | Minor |
| 983 | t(11;14) | NRAS | c.C181A | 2 | 47 | 94 | Major |
| 203 | t(11;14) | NRAS | c.C181A | 2 | 48 | 96 | Major |
| 482 | t(11;14) | NRAS | c.A182G | 2 | 16 | 32 | Minor |
| 1890 | t(4;14) | NRAS | c.A182G | 2 | 17 | 34 | Minor |
| 468 | t(11;14) | BRAF | c.T1799A | 2 | 46 | 92 | Major |
| 405 | t(4;14) | BRAF | c.T1799A | 3 | 12 | 36 | Minor |
| 983 | t(11;14) | DIS3 | c.G2249A | 2 | 46 | 92 | Major |
| 738 | t(4;14) | DIS3 | c.A1030C | 1 | 81 | 81 | Major |
| 468 | t(11;14) | DIS3 | c.A2765C | 1 | 69 | 69 | Major |
| 405 | t(4;14) | DIS3 | c.T1501G | 1 | 29 | 29 | Minor |
Calculated using copy number and SNV frequency.