Clinical characteristics of 136 patients with SMZL or chronic B-CLPD
| Characteristic . | SMZL (n = 84) . | B-CLPD (n = 52) . | ||
|---|---|---|---|---|
| Age (years), median (range) | 65.4 | (37 to 82) | 67.3 | 33.8 to 88.4 |
| Sex, number of patients (%) | ||||
| Males | 31 | (37) | 29 | (56) |
| Females | 53 | (63) | 23 | (44) |
| Leukemic disease, number of patients (%) | 60/82 | (73) | 52/52 | (100) |
| HCV-positive, number of patients (%) | 16/82 | (19) | 11/50 | (22) |
| Autoimmune background, number of patients (%) | 11/69 | (16) | 7/48 | (15) |
| Hemoglobin (g/dL), median (range) | 12.5 | (6.1 to 16.4) | 13.5 | (5.1 to 16.9) |
| Platelet count (×109/L), median (range) | 138 | (37 to 856) | 189 | (17 to 428) |
| LDH (U/L), median (range) | 401 | (199 to 2577) | 369 | (177 to 788) |
| β2-microglobulin (mcg/L), median (range) | 3475 | (1460 to 17900) | 2570 | (1440 to 5800) |
| Serum albumin (g/dL), median (range) | 4.2 | (2.2 to 5.2) | 4.3 | (3.3 to 5.1) |
| Serum MC, number of patients (%) | 31/77 | (40) | 18/49 | (37) |
| Type of monoclonal component, number of patients (%) | ||||
| Ig | 18/77 | (23) | 11/49 | (22) |
| IgG | 12/77 | (16) | 6/49 | (12) |
| k chain only | — | — | 1/49 | (2) |
| Not available | 1/77 | (1) | — | — |
| Type of light chain, number of patients (%) | ||||
| k | 21/77 | (27) | 12/49 | (24) |
| λ | 9/77 | (12) | 6/49 | (12) |
| Νot available | 1/77 | (1) | — | — |
| BM infiltration, median (range) (%) | 40 | (5 to 100) | 30 | (10 to 80) |
| Characteristic . | SMZL (n = 84) . | B-CLPD (n = 52) . | ||
|---|---|---|---|---|
| Age (years), median (range) | 65.4 | (37 to 82) | 67.3 | 33.8 to 88.4 |
| Sex, number of patients (%) | ||||
| Males | 31 | (37) | 29 | (56) |
| Females | 53 | (63) | 23 | (44) |
| Leukemic disease, number of patients (%) | 60/82 | (73) | 52/52 | (100) |
| HCV-positive, number of patients (%) | 16/82 | (19) | 11/50 | (22) |
| Autoimmune background, number of patients (%) | 11/69 | (16) | 7/48 | (15) |
| Hemoglobin (g/dL), median (range) | 12.5 | (6.1 to 16.4) | 13.5 | (5.1 to 16.9) |
| Platelet count (×109/L), median (range) | 138 | (37 to 856) | 189 | (17 to 428) |
| LDH (U/L), median (range) | 401 | (199 to 2577) | 369 | (177 to 788) |
| β2-microglobulin (mcg/L), median (range) | 3475 | (1460 to 17900) | 2570 | (1440 to 5800) |
| Serum albumin (g/dL), median (range) | 4.2 | (2.2 to 5.2) | 4.3 | (3.3 to 5.1) |
| Serum MC, number of patients (%) | 31/77 | (40) | 18/49 | (37) |
| Type of monoclonal component, number of patients (%) | ||||
| Ig | 18/77 | (23) | 11/49 | (22) |
| IgG | 12/77 | (16) | 6/49 | (12) |
| k chain only | — | — | 1/49 | (2) |
| Not available | 1/77 | (1) | — | — |
| Type of light chain, number of patients (%) | ||||
| k | 21/77 | (27) | 12/49 | (24) |
| λ | 9/77 | (12) | 6/49 | (12) |
| Νot available | 1/77 | (1) | — | — |
| BM infiltration, median (range) (%) | 40 | (5 to 100) | 30 | (10 to 80) |
HCV, hepatitis C virus; LDH, lactate dehydrogenase; MC, monoclonal component.