Table 1 Clinical characteristics of 11... | American Society of Hematology

Table 1

Clinical characteristics of 11 TAM patients

Patient no.	Gender	Period of gestation, wk	Weight at birth, g	PB at diagnosis of TAM				Cytogenetics International System for Human Cytogenetic Nomenclature (2009)	GATA1 mutation	Treatment		Clinical outcome	Onset of ML-DS (m of age)	Follow-up interval
Patient no.	Gender	Period of gestation, wk	Weight at birth, g	WBC, ×10³/µL	Blast, %	Hb, g/dL	Plt, ×10³/µL		GATA1 mutation	Exchange transfusion	Low-dose Ara-C	Clinical outcome	Onset of ML-DS (m of age)	Follow-up interval
1	F	36	3050	159	91	9.1	247	47,XX,+21 [20]	c.38_39delAG	No	Yes	Alive	Yes (14)	27
2	M	37	1868	45.0	65	19.0	80	47,XY,+21 [20]	c.49C>T	No	Yes	Alive	No	24
3	F	39	3102	40.3	37	15.1	304	47,XX,+21 [20]	c.59_174del116	No	No	Alive	No	23
4	M	37	2780	15.6	24	17.0	50	47,XY,+21 [20]	c.163_169del	No	No	Alive	No	22
5	M	39	3052	60.9	48	20.7	258	47,XY,+21 [19]	c.37G>T	No	No	Alive	No	21
6	F	37	2050	13.6	12	20.9	291	47,XX,+21 [20]	N/A	No	No	Alive	No	19
7	M	38	2694	280	87	13.6	26	47,XY,+21 [20]	c.186C>G	Yes	Yes	DOD	No	1
8	M	35	2070	174	80	19.2	117	47,XY,+21 [20]	c.-19-1G>A, c.1A>G	Yes	No	Alive	No	17
9	M	39	3380	56.2	65	20.2	156	47,XY,+21 [20]	c.35C>G	No	Yes	Alive	No	14
10	M	36	2131	199	84	12.2	73	47,XY,+21 [20]	c.19_20insCCTGA	Yes	Yes	Alive	No	14
11	F	33	2032	254	90	14.3	178	47,XX,+21 [20]	c.-19-62_-5delinsA	Yes	Yes	Alive	No	10

Patient no.	Gender	Period of gestation, wk	Weight at birth, g	PB at diagnosis of TAM				Cytogenetics International System for Human Cytogenetic Nomenclature (2009)	GATA1 mutation	Treatment		Clinical outcome	Onset of ML-DS (m of age)	Follow-up interval
Patient no.	Gender	Period of gestation, wk	Weight at birth, g	WBC, ×10³/µL	Blast, %	Hb, g/dL	Plt, ×10³/µL		GATA1 mutation	Exchange transfusion	Low-dose Ara-C	Clinical outcome	Onset of ML-DS (m of age)	Follow-up interval
1	F	36	3050	159	91	9.1	247	47,XX,+21 [20]	c.38_39delAG	No	Yes	Alive	Yes (14)	27
2	M	37	1868	45.0	65	19.0	80	47,XY,+21 [20]	c.49C>T	No	Yes	Alive	No	24
3	F	39	3102	40.3	37	15.1	304	47,XX,+21 [20]	c.59_174del116	No	No	Alive	No	23
4	M	37	2780	15.6	24	17.0	50	47,XY,+21 [20]	c.163_169del	No	No	Alive	No	22
5	M	39	3052	60.9	48	20.7	258	47,XY,+21 [19]	c.37G>T	No	No	Alive	No	21
6	F	37	2050	13.6	12	20.9	291	47,XX,+21 [20]	N/A	No	No	Alive	No	19
7	M	38	2694	280	87	13.6	26	47,XY,+21 [20]	c.186C>G	Yes	Yes	DOD	No	1
8	M	35	2070	174	80	19.2	117	47,XY,+21 [20]	c.-19-1G>A, c.1A>G	Yes	No	Alive	No	17
9	M	39	3380	56.2	65	20.2	156	47,XY,+21 [20]	c.35C>G	No	Yes	Alive	No	14
10	M	36	2131	199	84	12.2	73	47,XY,+21 [20]	c.19_20insCCTGA	Yes	Yes	Alive	No	14
11	F	33	2032	254	90	14.3	178	47,XX,+21 [20]	c.-19-62_-5delinsA	Yes	Yes	Alive	No	10

Brackets under International System for Human Cytogenetic Nomenclature indicate the number of analyzed cells in metaphase.

Ara-C, cytosine arabinoside; DOD, died of disease; Hb, hemoglobin; N/A, not assessed; Plt, platelet; WBC, white blood cell.