Table 2 CNAs and UPDs identified at... | American Society of Hematology

Table 2

CNAs and UPDs identified at diagnosis and relapse by SNP profiling

Aberration	Candidate genes in CDR	Diagnosis	Lost	Acquired	Relapse
del(9q21)	HNPRK, NTRK2	6	–3		3
UPD13q	FLT3	4	–1	+7	10
UPD1p	?	1	–1		0
Nonrecurrent CNAs at diagnosis		4	–2		2
gain(11q23.3)	MLL	0		+3	3
del(12p13)	ETV6	0		+3	3
del(11p13)	WT1	0		+3	3
del(17p)	TP53	0		+2	2
del(17q11.2)	NF1	0		+2	2
del(3p14.2)	FHIT	0		+2	2
del(4q22.1)	?	0		+2	2
Trisomy 5	?	0		+1	1
Monosomy 7	?	0		+1	1
Nonrecurrent CNAs at relapse		0		+22	22
Total		15	–7	+48	56

Aberration	Candidate genes in CDR	Diagnosis	Lost	Acquired	Relapse
del(9q21)	HNPRK, NTRK2	6	–3		3
UPD13q	FLT3	4	–1	+7	10
UPD1p	?	1	–1		0
Nonrecurrent CNAs at diagnosis		4	–2		2
gain(11q23.3)	MLL	0		+3	3
del(12p13)	ETV6	0		+3	3
del(11p13)	WT1	0		+3	3
del(17p)	TP53	0		+2	2
del(17q11.2)	NF1	0		+2	2
del(3p14.2)	FHIT	0		+2	2
del(4q22.1)	?	0		+2	2
Trisomy 5	?	0		+1	1
Monosomy 7	?	0		+1	1
Nonrecurrent CNAs at relapse		0		+22	22
Total		15	–7	+48	56

For the complete list, see supplementary Tables 1 to 3. CDR, commonly deleted region.