Clinical data at the time of the initial biopsies
| Group . | Number of patients . | WBC, median (range) . | PLT, median (range) . | HB, median (range) . | LDH, median (range) . | Cases with splenomegaly . | Cases with JAK2V617F (%) . |
|---|---|---|---|---|---|---|---|
| HC | 14 | 6.9 (3.7-10.0) | 242 (227-300) | 14 (12.0-14.6) | ns | ns | ns |
| RT | 10 | 9.1 (6.9-19.7) | 780 (503-1078) | 10 (8.9-13.5) | ns | ns | ns |
| PV | 33 | 11.2 (5.9-20.0) | 442 (266-897) | 19.0 (16.8-23.2) | 309 (174-689) | 13/18* | 100 |
| ET | 41 | 9.2 (1.6-18.4) | 801 (450-7400) | 14.2 (11.7-16.6) | 251 (181-339) | 4/15* | 51 |
| PMF | 39 | 10.5 (2.4-40.0) | 525 (15-1811) | 12.1 (6.7-15.5) | 447 (92-1455) | 13/18* | 59 |
| MPN,U-ET | 10 | 9.2 (5.1-12.9) | 809 (600-1696) | 15 (13.7-16.5) | 201 (142-275) | 2/9* | ns |
| MPN,U-PMF | 9 | 11.5 (8.9-18.4) | 790 (500-1056) | 14.0 (8.6-16.0) | 293 (184-401) | 5/8* | ns |
| ET-PMF | 7 | 9.0 (3.5-16.7) | 903 (602-1959) | 12.0 (5.5-14.0) | 364 (230-489) | 3/7* | ns |
| Group . | Number of patients . | WBC, median (range) . | PLT, median (range) . | HB, median (range) . | LDH, median (range) . | Cases with splenomegaly . | Cases with JAK2V617F (%) . |
|---|---|---|---|---|---|---|---|
| HC | 14 | 6.9 (3.7-10.0) | 242 (227-300) | 14 (12.0-14.6) | ns | ns | ns |
| RT | 10 | 9.1 (6.9-19.7) | 780 (503-1078) | 10 (8.9-13.5) | ns | ns | ns |
| PV | 33 | 11.2 (5.9-20.0) | 442 (266-897) | 19.0 (16.8-23.2) | 309 (174-689) | 13/18* | 100 |
| ET | 41 | 9.2 (1.6-18.4) | 801 (450-7400) | 14.2 (11.7-16.6) | 251 (181-339) | 4/15* | 51 |
| PMF | 39 | 10.5 (2.4-40.0) | 525 (15-1811) | 12.1 (6.7-15.5) | 447 (92-1455) | 13/18* | 59 |
| MPN,U-ET | 10 | 9.2 (5.1-12.9) | 809 (600-1696) | 15 (13.7-16.5) | 201 (142-275) | 2/9* | ns |
| MPN,U-PMF | 9 | 11.5 (8.9-18.4) | 790 (500-1056) | 14.0 (8.6-16.0) | 293 (184-401) | 5/8* | ns |
| ET-PMF | 7 | 9.0 (3.5-16.7) | 903 (602-1959) | 12.0 (5.5-14.0) | 364 (230-489) | 3/7* | ns |
WBC, white blood cell count ×106 per µL; PLT, platelet count ×106 per µL; HB, hemoglobin in g/dL; LDH, lactate dehydrogenase in U/L; ns, not specified.
Data were not available for the remainder of the patients.