Characteristics of peripheral blood and bone marrow dysplasia
| Cell lineage . | ||
|---|---|---|
| Erythroid . | Myeloid . | Megakaryocytic . |
| Peripheral blood | ||
| Anisocytosis | Granulocyte nuclear hypolobation (pseudo Pelger-Huet) | Platelet anisocytosis |
| Poikilocytosis | Granulocyte cytoplasmic hypogranulation/degranulation | Giant platelets |
| Basophilic stippling | Blasts | |
| Bone marrow | ||
| Binuclearity | Bizarre nuclear shapes | Large monolobular forms |
| Internuclear bridging | Nuclear hypolobation (pseudo Pelger-Huet) | Small binucleated elements |
| Irregular nuclear edges | Nuclear hypersegmentation | Dispersed nuclei |
| Megaloblastoid changes | Pseudo Chediak-Higashi granules | Micromegakaryocytes |
| Ring sideroblasts | Cytoplasmic hypogranulation /degranulation | Degranulation |
| Cytoplasmic inclusions | Anisocytosis | |
| Cytoplasmic bridging | ||
| Incomplete hemoglobinization | ||
| Fringed cytoplasm | ||
| Vacuolization | ||
| Cell lineage . | ||
|---|---|---|
| Erythroid . | Myeloid . | Megakaryocytic . |
| Peripheral blood | ||
| Anisocytosis | Granulocyte nuclear hypolobation (pseudo Pelger-Huet) | Platelet anisocytosis |
| Poikilocytosis | Granulocyte cytoplasmic hypogranulation/degranulation | Giant platelets |
| Basophilic stippling | Blasts | |
| Bone marrow | ||
| Binuclearity | Bizarre nuclear shapes | Large monolobular forms |
| Internuclear bridging | Nuclear hypolobation (pseudo Pelger-Huet) | Small binucleated elements |
| Irregular nuclear edges | Nuclear hypersegmentation | Dispersed nuclei |
| Megaloblastoid changes | Pseudo Chediak-Higashi granules | Micromegakaryocytes |
| Ring sideroblasts | Cytoplasmic hypogranulation /degranulation | Degranulation |
| Cytoplasmic inclusions | Anisocytosis | |
| Cytoplasmic bridging | ||
| Incomplete hemoglobinization | ||
| Fringed cytoplasm | ||
| Vacuolization | ||