Comparison of clinical characteristics between AA patients according to the STAT3 mutation status
| Variable . | AAs with STAT3 mutation, n = 16 . | AAs without STAT3 mutation, n = 124 . | P . |
|---|---|---|---|
| Age, years (median, range) | 48 | 41 | .8 |
| Sex, % | |||
| Male | 66 | 52 | .3 |
| Female | 34 | 48 | |
| Moderate severity, % | 29 | 21 | .3 |
| Presence of PNH clone, % | 54 | 38 | .2 |
| HLA-DR15, % | 75 | 44 | .02 |
| Any response to first line, % | 81 | 61 | .1 |
| Variable . | AAs with STAT3 mutation, n = 16 . | AAs without STAT3 mutation, n = 124 . | P . |
|---|---|---|---|
| Age, years (median, range) | 48 | 41 | .8 |
| Sex, % | |||
| Male | 66 | 52 | .3 |
| Female | 34 | 48 | |
| Moderate severity, % | 29 | 21 | .3 |
| Presence of PNH clone, % | 54 | 38 | .2 |
| HLA-DR15, % | 75 | 44 | .02 |
| Any response to first line, % | 81 | 61 | .1 |