Association of protein S with venous thrombotic risk factors in control subjects
| . | Free protein S . | Total protein S . | ||||||
|---|---|---|---|---|---|---|---|---|
| Subjects (n) . | Mean level (U/dL) . | Mean difference* (95% CI) . | Mean difference† (95% CI) . | Subjects (n) . | Mean level (U/dL) . | Mean difference* (95% CI) . | Mean difference† (95% CI) . | |
| No vitamin K antagonists | 2858 | 92 | Reference | Reference | 2910 | 102 | Reference | Reference |
| Vitamin K antagonists | 14 | 44 | −50 (−61 to −39) | −52 (−62 to −41) | 30 | 62 | −37 (−48 to −28) | −40 (−49 to −30) |
| Nonestrogen users (women) | 1067 | 88 | Reference | Reference | 1097 | 105 | Reference | Reference |
| Estrogen users (women) | 408 | 79 | −4 (−6 to −1) | −7 (−9 to −5) | 412 | 89 | −9 (−12 to −7) | −11 (−13 to −9) |
| No pregnancy/puerperium (women) | 1473 | 86 | Reference | Reference | 1505 | 101 | Reference | Reference |
| Pregnancy/puerperium (women) | 28 | 70 | −6 (−13 to 2) | −14 (−21 to −6) | 29 | 89 | 1 (−6 to 8) | −7 (−14 to −0.1) |
| Normal weight | 1332 | 87 | Reference | Reference | 1354 | 98 | Reference | Reference |
| Overweight | 1072 | 96 | 6 (4 to 7) | 6 (4 to 7) | 1109 | 105 | 5 (4 to 7) | 5 (3 to 6) |
| Obesity | 358 | 97 | 8 (6 to 11) | 8 (6 to 11) | 365 | 108 | 8 (6 to 10) | 8 (5 to 10) |
| . | Free protein S . | Total protein S . | ||||||
|---|---|---|---|---|---|---|---|---|
| Subjects (n) . | Mean level (U/dL) . | Mean difference* (95% CI) . | Mean difference† (95% CI) . | Subjects (n) . | Mean level (U/dL) . | Mean difference* (95% CI) . | Mean difference† (95% CI) . | |
| No vitamin K antagonists | 2858 | 92 | Reference | Reference | 2910 | 102 | Reference | Reference |
| Vitamin K antagonists | 14 | 44 | −50 (−61 to −39) | −52 (−62 to −41) | 30 | 62 | −37 (−48 to −28) | −40 (−49 to −30) |
| Nonestrogen users (women) | 1067 | 88 | Reference | Reference | 1097 | 105 | Reference | Reference |
| Estrogen users (women) | 408 | 79 | −4 (−6 to −1) | −7 (−9 to −5) | 412 | 89 | −9 (−12 to −7) | −11 (−13 to −9) |
| No pregnancy/puerperium (women) | 1473 | 86 | Reference | Reference | 1505 | 101 | Reference | Reference |
| Pregnancy/puerperium (women) | 28 | 70 | −6 (−13 to 2) | −14 (−21 to −6) | 29 | 89 | 1 (−6 to 8) | −7 (−14 to −0.1) |
| Normal weight | 1332 | 87 | Reference | Reference | 1354 | 98 | Reference | Reference |
| Overweight | 1072 | 96 | 6 (4 to 7) | 6 (4 to 7) | 1109 | 105 | 5 (4 to 7) | 5 (3 to 6) |
| Obesity | 358 | 97 | 8 (6 to 11) | 8 (6 to 11) | 365 | 108 | 8 (6 to 10) | 8 (5 to 10) |