WHO classification of myeloid neoplasms
| Major subgroups . | Conditions . |
|---|---|
| MDS | Refractory cytopenia with unilineage dysplasia, RARS, refractory cytopenia with multilineage dysplasia (RCMD), refractory cytopenia with excess blasts (RAEB, type 1 and 2), MDS with isolated del(5q) |
| Myeloproliferative neoplasms (MPN) | Chronic myeloid leukemia (CML, BCR-ABL1 positive), chronic neutrophilic leukemia (CNL), polycythemia vera, essential thrombocythemia, primary myelofibrosis (PMF), chronic eosinophilic leukemia, mastocytosis |
| MDS/MPN | CMML, atypical chronic myeloid leukemia (aCML, BCR-ABL1 negative), juvenile myelomonocytic leukemia (JMML), RARS-T |
| AML | Various subtypes based on blast morphology and/or underlying genetic lesion(s) |
| Major subgroups . | Conditions . |
|---|---|
| MDS | Refractory cytopenia with unilineage dysplasia, RARS, refractory cytopenia with multilineage dysplasia (RCMD), refractory cytopenia with excess blasts (RAEB, type 1 and 2), MDS with isolated del(5q) |
| Myeloproliferative neoplasms (MPN) | Chronic myeloid leukemia (CML, BCR-ABL1 positive), chronic neutrophilic leukemia (CNL), polycythemia vera, essential thrombocythemia, primary myelofibrosis (PMF), chronic eosinophilic leukemia, mastocytosis |
| MDS/MPN | CMML, atypical chronic myeloid leukemia (aCML, BCR-ABL1 negative), juvenile myelomonocytic leukemia (JMML), RARS-T |
| AML | Various subtypes based on blast morphology and/or underlying genetic lesion(s) |
Information is from Swerdlow et al.1 The WHO classification of myeloid neoplasms also includes myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1.