Viral and cellular targets and functions of EBV miRNAs
| Targets . | EBV-miRNA . | Function of EBV-miRNA . | Reference . |
|---|---|---|---|
| Viral targets | |||
| BALF5 | EBV-miR-BART2 | Inhibition of lytic cycle | 89 |
| EBNA2 | EBV-miR-BART6 | Maintenance of viral latency | 90 |
| LMP1 | EBV-miR-BART-Cluster1 | Growth control or escape from immunosurveillance | 59,91 |
| EBV-miR-BART19-5p | Prevent apoptosis | 59 | |
| LMP2A | EBV-miR-BART22 | Growth control or escape from immunosurveillance | 92 |
| Cellular targets | |||
| Dicer | EBV-miR-BART6 | Promote latency | 90 |
| Bim | EBV-miR-BART-Cluster 1 | Anti-apoptosis | 93 |
| EBV-miR-BART-Cluster 2 | Anti-apoptosis | 93 | |
| CXCL-11/I-TAC | EBV-miR-BHRF1-3 | Anti-apoptosis | 94 |
| PUMA | EBV-miR-BART5 | Anti-apoptosis | 55,93 |
| IPO7 | EBV-miR-BART3-3p | Anti-inflammation | 59,95 |
| TOMM22 | EBV-miR-BART16-5p | Anti-apoptosis | 59,95 |
| MICB | EBV-miR-BART2-5p | Immune evasion | 96 |
| BCLAF1 | EBV-miR-BART17-5p | Anti-apoptosis | 59 |
| CLEC2D (LLT1) | EBV-miR-BART3-3p | Immune evasion | 52 |
| EBV-miR-BART1-3p | Immune evasion | 52 | |
| LY75 (DEC205) | EBV-miR-BART1-5p | Immune evasion | 52 |
| CLEC7A (Dectin-1) | EBV-miR-BART4 | Immune evasion | 52 |
| CLEC2B (AICL) | EBV-miR-BART2-5p | Immune evasion | 52 |
| NLRP3 | EBV-miR-BART15 | Immune dysregulation | 97 |
| Targets . | EBV-miRNA . | Function of EBV-miRNA . | Reference . |
|---|---|---|---|
| Viral targets | |||
| BALF5 | EBV-miR-BART2 | Inhibition of lytic cycle | 89 |
| EBNA2 | EBV-miR-BART6 | Maintenance of viral latency | 90 |
| LMP1 | EBV-miR-BART-Cluster1 | Growth control or escape from immunosurveillance | 59,91 |
| EBV-miR-BART19-5p | Prevent apoptosis | 59 | |
| LMP2A | EBV-miR-BART22 | Growth control or escape from immunosurveillance | 92 |
| Cellular targets | |||
| Dicer | EBV-miR-BART6 | Promote latency | 90 |
| Bim | EBV-miR-BART-Cluster 1 | Anti-apoptosis | 93 |
| EBV-miR-BART-Cluster 2 | Anti-apoptosis | 93 | |
| CXCL-11/I-TAC | EBV-miR-BHRF1-3 | Anti-apoptosis | 94 |
| PUMA | EBV-miR-BART5 | Anti-apoptosis | 55,93 |
| IPO7 | EBV-miR-BART3-3p | Anti-inflammation | 59,95 |
| TOMM22 | EBV-miR-BART16-5p | Anti-apoptosis | 59,95 |
| MICB | EBV-miR-BART2-5p | Immune evasion | 96 |
| BCLAF1 | EBV-miR-BART17-5p | Anti-apoptosis | 59 |
| CLEC2D (LLT1) | EBV-miR-BART3-3p | Immune evasion | 52 |
| EBV-miR-BART1-3p | Immune evasion | 52 | |
| LY75 (DEC205) | EBV-miR-BART1-5p | Immune evasion | 52 |
| CLEC7A (Dectin-1) | EBV-miR-BART4 | Immune evasion | 52 |
| CLEC2B (AICL) | EBV-miR-BART2-5p | Immune evasion | 52 |
| NLRP3 | EBV-miR-BART15 | Immune dysregulation | 97 |