Summary statistics for 48- and 72-h NSAA data for each course of therapy
Trough time (h) . | Cycle . | Acceptable data . | NSAA (IU/mL) . | NSAA ≥0.10 IU/mL . | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Patients . | Samples . | Patients . | Samples . | ||||||||
No. . | % . | No. . | % . | Median . | Range . | No. . | % . | No. . | % . | ||
48 | 1 | 50 | 90.9 | 155 | 72.4 | 0.715 | <LOQ-2.884 | 50 | 100 | 151 | 97.4 |
48 | 2 | 25 | 58.1 | 28 | 56.0 | 0.654 | <LOQ-1.294 | 23 | 92.0 | 26 | 92.9 |
48 | 3 | 29 | 90.6 | 37 | 88.1 | 0.551 | 0.099-1.429 | 28 | 96.6 | 36 | 97.3 |
48 | 4 | 16 | 66.7 | 24 | 70.6 | 0.418 | 0.080-1.635 | 16 | 100 | 23 | 95.8 |
48 | ≥5 | 12 | 75.0 | 19 | 51.4 | 0.669 | <LOQ-1.114 | 10 | 83.3 | 16 | 84.2 |
48 | All | 52 | 94.5 | 263 | 69.8 | 0.645 | <LOQ-2.884 | 52 | 100 | 252 | 95.8 |
72 | 1 | 50 | 90.9 | 86 | 79.6 | 0.251 | 0.043-1-612 | 49 | 98.0 | 73 | 84.9 |
72 | 2 | 19 | 57.6 | 19 | 57.6 | 0.248 | <LOQ-0.873 | 15 | 78.9 | 15 | 78.9 |
72 | 3 | 18 | 90.0 | 18 | 90.0 | 0.163 | 0.030-0.741 | 16 | 88.9 | 16 | 88.9 |
72 | 4 | 7 | 53.8 | 7 | 53.8 | 0.475 | <LOQ-0.622 | 6 | 85.7 | 6 | 85.7 |
72 | ≥5 | 11 | 78.6 | 18 | 62.1 | 0.245 | 0.087-0.717 | 10 | 90.9 | 15 | 83.3 |
72 | All | 52 | 94.5 | 148 | 72.9 | 0.248 | <LOQ-1.612 | 52 | 100 | 125 | 84.5 |
Trough time (h) . | Cycle . | Acceptable data . | NSAA (IU/mL) . | NSAA ≥0.10 IU/mL . | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Patients . | Samples . | Patients . | Samples . | ||||||||
No. . | % . | No. . | % . | Median . | Range . | No. . | % . | No. . | % . | ||
48 | 1 | 50 | 90.9 | 155 | 72.4 | 0.715 | <LOQ-2.884 | 50 | 100 | 151 | 97.4 |
48 | 2 | 25 | 58.1 | 28 | 56.0 | 0.654 | <LOQ-1.294 | 23 | 92.0 | 26 | 92.9 |
48 | 3 | 29 | 90.6 | 37 | 88.1 | 0.551 | 0.099-1.429 | 28 | 96.6 | 36 | 97.3 |
48 | 4 | 16 | 66.7 | 24 | 70.6 | 0.418 | 0.080-1.635 | 16 | 100 | 23 | 95.8 |
48 | ≥5 | 12 | 75.0 | 19 | 51.4 | 0.669 | <LOQ-1.114 | 10 | 83.3 | 16 | 84.2 |
48 | All | 52 | 94.5 | 263 | 69.8 | 0.645 | <LOQ-2.884 | 52 | 100 | 252 | 95.8 |
72 | 1 | 50 | 90.9 | 86 | 79.6 | 0.251 | 0.043-1-612 | 49 | 98.0 | 73 | 84.9 |
72 | 2 | 19 | 57.6 | 19 | 57.6 | 0.248 | <LOQ-0.873 | 15 | 78.9 | 15 | 78.9 |
72 | 3 | 18 | 90.0 | 18 | 90.0 | 0.163 | 0.030-0.741 | 16 | 88.9 | 16 | 88.9 |
72 | 4 | 7 | 53.8 | 7 | 53.8 | 0.475 | <LOQ-0.622 | 6 | 85.7 | 6 | 85.7 |
72 | ≥5 | 11 | 78.6 | 18 | 62.1 | 0.245 | 0.087-0.717 | 10 | 90.9 | 15 | 83.3 |
72 | All | 52 | 94.5 | 148 | 72.9 | 0.248 | <LOQ-1.612 | 52 | 100 | 125 | 84.5 |
LOQ, limit of quantitation.