Table 2 Comparison of survival after... | American Society of Hematology

Table 2

Comparison of survival after transplantation of double unit UCBT with that of adult donors

Series	Patients, n	Conditioning	Graft source	Follow-up, y	Median age, y	Survival (PFS or DFS), %	Comment
Brunstein, Blood 2010,⁶⁶ leukemia	128	Myelo	UCB	5	25	51	UCB similar to MRD, MUD
	204	Ablative	MRD		40	33
	152		MUD		31	48
	52		MMUD		31	38
Ponce, BBMT 2011,⁶⁷ heme malignancy	75	Myelo	UCBT	2	37	55	UCB similar to MUD
	108	Ablative	MRD		47	66
	184		MUD		48	55
Brunstein, Blood 2011,⁶⁹ leukemia and lymphoma	50	RIC	UCB	1	58	46	Now a randomized Clinical Trials Network study
Brunstein, Blood 2011,⁶⁹ leukemia and lymphoma	50	RIC	haplo BM	1	48	48	Now a randomized Clinical Trials Network study
Chen, BBMT 2012,⁶⁸ hematologic malignancy	64	RIC	dUCB	3	53	30	UCB similar to MUD
Chen, BBMT 2012,⁶⁸ hematologic malignancy	221	RIC	MUD	3	58	40	UCB similar to MUD

Series	Patients, n	Conditioning	Graft source	Follow-up, y	Median age, y	Survival (PFS or DFS), %	Comment
Brunstein, Blood 2010,⁶⁶ leukemia	128	Myelo	UCB	5	25	51	UCB similar to MRD, MUD
	204	Ablative	MRD		40	33
	152		MUD		31	48
	52		MMUD		31	38
Ponce, BBMT 2011,⁶⁷ heme malignancy	75	Myelo	UCBT	2	37	55	UCB similar to MUD
	108	Ablative	MRD		47	66
	184		MUD		48	55
Brunstein, Blood 2011,⁶⁹ leukemia and lymphoma	50	RIC	UCB	1	58	46	Now a randomized Clinical Trials Network study
Brunstein, Blood 2011,⁶⁹ leukemia and lymphoma	50	RIC	haplo BM	1	48	48	Now a randomized Clinical Trials Network study
Chen, BBMT 2012,⁶⁸ hematologic malignancy	64	RIC	dUCB	3	53	30	UCB similar to MUD
Chen, BBMT 2012,⁶⁸ hematologic malignancy	221	RIC	MUD	3	58	40	UCB similar to MUD

PFS, progression-free survival.