Table 1.

Demographics and disease characteristics

All treated (N = 53)Secondary AML (N = 24)
Median age, y (range) 75 (60-87) 77 (60-87) 
Sex, male, % 64 75 
ECOG, %   
 0, 19 13 
 1 79 88 
MRC cytogenetic risk, %   
 Favorable 
 Intermediate 62 25 
 Adverse 38 75 
Underlying myelodysplasia, % 43 54 
Baseline BM blast, %, median (range) 52·5 (20-90) 34 (20-90) 
Baseline WBC ×103/µL, median (range) 2.1 (0.4-132) 1.5 (0.8-18.9) 
All treated (N = 53)Secondary AML (N = 24)
Median age, y (range) 75 (60-87) 77 (60-87) 
Sex, male, % 64 75 
ECOG, %   
 0, 19 13 
 1 79 88 
MRC cytogenetic risk, %   
 Favorable 
 Intermediate 62 25 
 Adverse 38 75 
Underlying myelodysplasia, % 43 54 
Baseline BM blast, %, median (range) 52·5 (20-90) 34 (20-90) 
Baseline WBC ×103/µL, median (range) 2.1 (0.4-132) 1.5 (0.8-18.9) 

BM, bone marrow; WBC, white blood count.

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