Characteristics of patients who evolved while on eltrombopag
Patient # . | Age (y) . | Response . | Baseline . | At evolution . | Time on eltrombopag (mo) . | Dysplasia . | Outcome . | Time posttransplant (mo) . |
---|---|---|---|---|---|---|---|---|
7 | 60 | NR | 46XY[20] | −7[20] | 3 | N | Died of progressive cytopenias | N/A |
8 | 18 | NR | 46XX[6] | +8[9]/46XX[11] | 3 | N | Transplanted successfully | 31 |
19 | 20 | NR | 46XY[20] | −7[5]t(1;16) [3]/46XY[12] | 3 | N | Transplanted successfully | 18 |
26 | 67 | R | 46XY[20] | del(13)[19]/46XY[1] | 13 | Mild dyserythropoeisis | Transplanted | 8 |
31 | 41 | NR | 46XY[20] | +21[3]/46XY[17] −7[2]/46XY[19] | 3 6 | Mild dyserythropoeisis | Awaiting transplant | N/A |
32 | 66 | R | 46XY[20] | 46XYdel13q[2]/46XY[18] | 9 | N | Under observation | N/A |
36 | 23 | NR | 46XY[20] | −7[5],XY[15] | 3 | N | Transplanted successfully | 3 |
42 | 17 | NR | No metaphases | +1,der(1;7) [4]/46XY[16] | 3 | N | Transplanted successfully | 4 |
Patient # . | Age (y) . | Response . | Baseline . | At evolution . | Time on eltrombopag (mo) . | Dysplasia . | Outcome . | Time posttransplant (mo) . |
---|---|---|---|---|---|---|---|---|
7 | 60 | NR | 46XY[20] | −7[20] | 3 | N | Died of progressive cytopenias | N/A |
8 | 18 | NR | 46XX[6] | +8[9]/46XX[11] | 3 | N | Transplanted successfully | 31 |
19 | 20 | NR | 46XY[20] | −7[5]t(1;16) [3]/46XY[12] | 3 | N | Transplanted successfully | 18 |
26 | 67 | R | 46XY[20] | del(13)[19]/46XY[1] | 13 | Mild dyserythropoeisis | Transplanted | 8 |
31 | 41 | NR | 46XY[20] | +21[3]/46XY[17] −7[2]/46XY[19] | 3 6 | Mild dyserythropoeisis | Awaiting transplant | N/A |
32 | 66 | R | 46XY[20] | 46XYdel13q[2]/46XY[18] | 9 | N | Under observation | N/A |
36 | 23 | NR | 46XY[20] | −7[5],XY[15] | 3 | N | Transplanted successfully | 3 |
42 | 17 | NR | No metaphases | +1,der(1;7) [4]/46XY[16] | 3 | N | Transplanted successfully | 4 |
N/A, not applicable; NR, nonresponder; R, responder.