Demographics of the population in study: 100 patients with PMF of the COMFORT-2 cohort at the time of enrollment and 350 patients with PMF of the DIPSS cohort at the time of diagnosis
. | COMFORT-2 . | DIPSS . |
---|---|---|
Number of patients | 100 | 350 |
Age, y, median (range) | 68 (35-85)* | 67 (29-90) |
Male/female | 61/39 | 234/116 |
Leukocyte count, ×109/L, median (range) | 11.1 (2.5-111.6) | 10 (0.8-106.1) |
Circulating blast cells, % | 2 (0-8) | 0 (0-9) |
Hemoglobin, g/dL, median (range) | 10.3 (5.4-15.8) | 10.3 (4.0-16.4) |
Platelet count, ×109/L, median (range) | 235 (101-918) | 248 (10-1900) |
Spleen from left costal margin, cm | 15 (5-29) | 5 (0-24) |
. | COMFORT-2 . | DIPSS . |
---|---|---|
Number of patients | 100 | 350 |
Age, y, median (range) | 68 (35-85)* | 67 (29-90) |
Male/female | 61/39 | 234/116 |
Leukocyte count, ×109/L, median (range) | 11.1 (2.5-111.6) | 10 (0.8-106.1) |
Circulating blast cells, % | 2 (0-8) | 0 (0-9) |
Hemoglobin, g/dL, median (range) | 10.3 (5.4-15.8) | 10.3 (4.0-16.4) |
Platelet count, ×109/L, median (range) | 235 (101-918) | 248 (10-1900) |
Spleen from left costal margin, cm | 15 (5-29) | 5 (0-24) |
The median age at diagnosis was 61 years (y) (range, 27-76).