List of top 50 genes downregulated by IL-4 in monocyte-derived macrophages
| Gene symbol . | Name . | Fold change . |
|---|---|---|
| Mamdc2 | MAM domain containing 2 | 0.0148 |
| Apoe | Apolipoprotein E | 0.0148 |
| Dio2 | Deiodinase, iodothyronine, type II | 0.0169 |
| AF251705 | cDNA sequence AF251705 | 0.0211 |
| Cdkn1c | Cyclin-dependent kinase inhibitor 1C (P57) | 0.0226 |
| Hpgds | Hematopoietic prostaglandin D synthase | 0.0232 |
| Syt10 | Synaptotagmin X | 0.0287 |
| C77080 | Expressed sequence C77080 | 0.0338 |
| Mmp27 | Matrix metallopeptidase 27 | 0.0356 |
| Mcoln3 | Mucolipin 3 | 0.0364 |
| Tspan7 | Tetraspanin 7 | 0.0368 |
| Htra1 | HtrA serine peptidase 1 | 0.0371 |
| Saa3 | Serum amyloid A 3 | 0.0373 |
| Clec4d | C-type lectin domain family 4, member d | 0.0390 |
| Cd200 | CD200 antigen | 0.0412 |
| Ms4a7 | Membrane-spanning 4-domains, subfamily A, member 7 | 0.0413 |
| Sh2d3c | SH2 domain containing 3C | 0.0430 |
| Htr2b | 5-Hydroxytryptamine (serotonin) receptor 2B | 0.0452 |
| Reps2 | RALBP1 associated Eps domain containing protein 2 | 0.0489 |
| Npy | Neuropeptide Y | 0.0494 |
| Cnrip1 | Cannabinoid receptor interacting protein 1 | 0.0495 |
| Tmem140 | Transmembrane protein 140 | 0.0502 |
| Lhfpl2 | Lipoma HMGIC fusion partner-like 2 | 0.0503 |
| Arhgap22 | ρ GTPase activating protein 22 | 0.0507 |
| Prss46 | Protease, serine 46 | 0.0512 |
| Spp1 | Secreted phosphoprotein 1 | 0.0513 |
| Cd93 | CD93 antigen | 0.0519 |
| Pcp4l1 | Purkinje cell protein 4-like 1 | 0.0525 |
| Mfge8 | Milk fat globule-EGF factor 8 protein | 0.0547 |
| Gstm1 | Glutathione S-transferase, μ 1 | 0.0547 |
| Gpr137b | G protein-coupled receptor 137B | 0.0576 |
| Cd109 | CD109 antigen | 0.0581 |
| Tspan13 | Tetraspanin 13 | 0.0586 |
| Gas6 | Growth arrest specific 6 | 0.0587 |
| 4930404N11Rik | RIKEN cDNA 4930404N11 gene | 0.0631 |
| Mpeg1 | Macrophage expressed gene 1 | 0.0655 |
| Tecpr1 | Tectonin β-propeller repeat containing 1 | 0.0680 |
| Gprc5b | G protein-coupled receptor, family C, group 5, member B | 0.0703 |
| Pianp | PILR α associated neural protein | 0.0707 |
| Gpr137b-ps | G protein-coupled receptor 137B, pseudogene | 0.0734 |
| Gdpd1 | Glycerophosphodiester phosphodiesterase domain containing 1 | 0.0742 |
| Lrrc27 | Leucine rich repeat containing 27 | 0.0748 |
| Fstl1 | Follistatin-like 1 | 0.0750 |
| Pdzk1ip1 | PDZK1 interacting protein 1 | 0.0759 |
| Fhdc1 | FH2 domain containing 1 | 0.0765 |
| Itgb5 | Integrin β 5 | 0.0792 |
| Speg | SPEG complex locus | 0.0795 |
| Gstm3 | Glutathione S-transferase, μ 3 | 0.0799 |
| Rgs1 | Regulator of G-protein signaling 1 | 0.0805 |
| Gene symbol . | Name . | Fold change . |
|---|---|---|
| Mamdc2 | MAM domain containing 2 | 0.0148 |
| Apoe | Apolipoprotein E | 0.0148 |
| Dio2 | Deiodinase, iodothyronine, type II | 0.0169 |
| AF251705 | cDNA sequence AF251705 | 0.0211 |
| Cdkn1c | Cyclin-dependent kinase inhibitor 1C (P57) | 0.0226 |
| Hpgds | Hematopoietic prostaglandin D synthase | 0.0232 |
| Syt10 | Synaptotagmin X | 0.0287 |
| C77080 | Expressed sequence C77080 | 0.0338 |
| Mmp27 | Matrix metallopeptidase 27 | 0.0356 |
| Mcoln3 | Mucolipin 3 | 0.0364 |
| Tspan7 | Tetraspanin 7 | 0.0368 |
| Htra1 | HtrA serine peptidase 1 | 0.0371 |
| Saa3 | Serum amyloid A 3 | 0.0373 |
| Clec4d | C-type lectin domain family 4, member d | 0.0390 |
| Cd200 | CD200 antigen | 0.0412 |
| Ms4a7 | Membrane-spanning 4-domains, subfamily A, member 7 | 0.0413 |
| Sh2d3c | SH2 domain containing 3C | 0.0430 |
| Htr2b | 5-Hydroxytryptamine (serotonin) receptor 2B | 0.0452 |
| Reps2 | RALBP1 associated Eps domain containing protein 2 | 0.0489 |
| Npy | Neuropeptide Y | 0.0494 |
| Cnrip1 | Cannabinoid receptor interacting protein 1 | 0.0495 |
| Tmem140 | Transmembrane protein 140 | 0.0502 |
| Lhfpl2 | Lipoma HMGIC fusion partner-like 2 | 0.0503 |
| Arhgap22 | ρ GTPase activating protein 22 | 0.0507 |
| Prss46 | Protease, serine 46 | 0.0512 |
| Spp1 | Secreted phosphoprotein 1 | 0.0513 |
| Cd93 | CD93 antigen | 0.0519 |
| Pcp4l1 | Purkinje cell protein 4-like 1 | 0.0525 |
| Mfge8 | Milk fat globule-EGF factor 8 protein | 0.0547 |
| Gstm1 | Glutathione S-transferase, μ 1 | 0.0547 |
| Gpr137b | G protein-coupled receptor 137B | 0.0576 |
| Cd109 | CD109 antigen | 0.0581 |
| Tspan13 | Tetraspanin 13 | 0.0586 |
| Gas6 | Growth arrest specific 6 | 0.0587 |
| 4930404N11Rik | RIKEN cDNA 4930404N11 gene | 0.0631 |
| Mpeg1 | Macrophage expressed gene 1 | 0.0655 |
| Tecpr1 | Tectonin β-propeller repeat containing 1 | 0.0680 |
| Gprc5b | G protein-coupled receptor, family C, group 5, member B | 0.0703 |
| Pianp | PILR α associated neural protein | 0.0707 |
| Gpr137b-ps | G protein-coupled receptor 137B, pseudogene | 0.0734 |
| Gdpd1 | Glycerophosphodiester phosphodiesterase domain containing 1 | 0.0742 |
| Lrrc27 | Leucine rich repeat containing 27 | 0.0748 |
| Fstl1 | Follistatin-like 1 | 0.0750 |
| Pdzk1ip1 | PDZK1 interacting protein 1 | 0.0759 |
| Fhdc1 | FH2 domain containing 1 | 0.0765 |
| Itgb5 | Integrin β 5 | 0.0792 |
| Speg | SPEG complex locus | 0.0795 |
| Gstm3 | Glutathione S-transferase, μ 3 | 0.0799 |
| Rgs1 | Regulator of G-protein signaling 1 | 0.0805 |