Table 3 Second malignancies in young HCL... | American Society of Hematology

Table 3

Second malignancies in young HCL patients after cladribine treatment

Patient	Second cancer	HCL therapy before cladribine	Age (y) at diagnosis of second cancer	Time (mo) from diagnosis of HCL to second cancer	Time (mo) from cladribine to second cancer	Survival (mo) from diagnosis of HCL	Survival (mo) after diagnosis of second cancer	Status
1	Adenocarcinoma, colon	Splenectomy	53	178	1	284	106	Alive
2	Adenocarcinoma, prostate	Splenectomy, interferon, chlorambucil	64	314	122	385	71	Dead
2	Adenocarcinoma, colon	Splenectomy, interferon, chlorambucil	61	281	89	385	104	Dead
2	Adenocarcinoma, pancreas	Splenectomy, interferon, chlorambucil	69	375	183	385	11	Dead
3	Non-Hodgkin lymphoma	IFN, G-CSF	65	301	236	337	37	Alive
4	Metastatic renal cell carcinoma	Splenectomy, IFN, chlorambucil, prednisone	59	353	206	354	1	Dead
5	CML	None	49	163	136	277	115	Alive
5	Non-Hodgkin lymphoma (follicular)	None	54	223	196	277	55	Alive
6	Adenocarcinoma, prostate	None	58	243	239	244	1	Alive
7	Acute myeloid leukemia – FAB M2	IFN, prednisone	60	327	63	334	7	Dead
8	Acute myeloid leukemia	Splenectomy, chlorambucil	61	395	247	402	7	Dead

Patient	Second cancer	HCL therapy before cladribine	Age (y) at diagnosis of second cancer	Time (mo) from diagnosis of HCL to second cancer	Time (mo) from cladribine to second cancer	Survival (mo) from diagnosis of HCL	Survival (mo) after diagnosis of second cancer	Status
1	Adenocarcinoma, colon	Splenectomy	53	178	1	284	106	Alive
2	Adenocarcinoma, prostate	Splenectomy, interferon, chlorambucil	64	314	122	385	71	Dead
2	Adenocarcinoma, colon	Splenectomy, interferon, chlorambucil	61	281	89	385	104	Dead
2	Adenocarcinoma, pancreas	Splenectomy, interferon, chlorambucil	69	375	183	385	11	Dead
3	Non-Hodgkin lymphoma	IFN, G-CSF	65	301	236	337	37	Alive
4	Metastatic renal cell carcinoma	Splenectomy, IFN, chlorambucil, prednisone	59	353	206	354	1	Dead
5	CML	None	49	163	136	277	115	Alive
5	Non-Hodgkin lymphoma (follicular)	None	54	223	196	277	55	Alive
6	Adenocarcinoma, prostate	None	58	243	239	244	1	Alive
7	Acute myeloid leukemia – FAB M2	IFN, prednisone	60	327	63	334	7	Dead
8	Acute myeloid leukemia	Splenectomy, chlorambucil	61	395	247	402	7	Dead

CML, chronic myelogenous leukemia; G-CSF, granulocyte colony-stimulating factor; IFN, interferon.