Outcomes of new pregnancies in APS women and in control women
| Group, N . | APS, 517 . | . | Control, 796 . | . | . | . |
|---|---|---|---|---|---|---|
| N | Incidence | N | Incidence | RR, 95%CI | P | |
| New pregnancies | 513 | 0.992 | 791 | 0.994 | ||
| Spontaneous abortions before 10 WG | 91 | 0.177 | 175 | 0.221 | 0.802 (0.639-1.007) | .0572 |
| Ongoing pregnancies at 10 WG | 422 | 0.823 | 621 | 0.785 | 1.048 (0.993-1.106) | .0917 |
| Fetal losses (% of new pregnancies) | 66 | 0.129 | 81 | 0.102 | 1.256 (0.926-1.705) | .143 |
| Fetal losses (% of ongoing pregnancies at 10 WG) | 66 | 0.156 | 81 | 0.130 | 1.199 (0.888-1.620) | .237 |
| Ongoing pregnancy at 20 WG (% of new pregnancies) | 387 | 0.754 | 567 | 0.717 | 1.052 (0.985-1.124) | .129 |
| Live births (% of new pregnancies) | 357 | 0.696 | 540 | 0.683 | 1.019 (0.946-1.098) | .613 |
| Live births (% of ongoing pregnancies at 10 WG) | 357 | 0.846 | 540 | 0.870 | 0.973 (0.925-1.024) | .289 |
| Preterm live births <37 WG (% of live births) | 89 | 0.249 | 74 | 0.137 | 1.819 (1.378-2.402) | <.0001 |
| Preterm live births <34 WG (% of live births) | 44 | 0.123 | 32 | 0.059 | 2.080 (1.346-3.214) | .0010 |
| PE (% of ongoing pregnancies at 20 WG) | 57 | 0.147 | 32 | 0.056 | 2.610 (1.726-4.550) | <.0001 |
| Severe PE | 40 | 0.103 | 21 | 0.037 | 2.791 (1.672-4.657) | .0001 |
| PE <34 WG | 38 | 0.098 | 15 | 0.026 | 3.712 (2.071-6.653) | <.0001 |
| Eclampsia | 12 | 0.031 | 8 | 0.014 | 2.198 (0.907-5.326) | .0813 |
| HELLP syndrome | 16 | 0.045 | 6 | 0.011 | 3.907 (1.543-9.896) | .0041 |
| SGA (% of ongoing pregnancies at 20 WG) | 73 | 0.395 | 80 | 0.141 | 1.337 (1,001-1;786) | .0495 |
| Severe SGA <p5 | 37 | 0.096 | 40 | 0.071 | 1.355 (0.883-2.079) | .164 |
| Very severe SGA <p3 | 26 | 0.067 | 25 | 0.044 | 1.524 (0.894-2.598) | .122 |
| PE + SGA | 39 | 0.100 | 20 | 0.035 | 2.857 (1.693-4.822) | .0001 |
| PA (% of ongoing pregnancies at 20 WG) | 12 | 0.031 | 11 | 0.019 | 1.598 (0.713-3.585) | .255 |
| Placenta-mediated complications: PE and/or SGA and/or PA (% of ongoing pregnancies at 20 WG) | 98 | 0.253 | 99 | 0.175 | 1.450 (1.132-1.858) | .0032 |
| NM (% of live births) | 18 | 0.047 | 8 | 0.014 | 3.529 (1.551-8.031) | .0026 |
| Early NM, day 1-7 | 9 | 0.023 | 5 | 0.009 | 2.723 (0.920-8.058) | .0704 |
| Late NM, day 8-27 | 9 | 0.023 | 3 | 0.005 | 4.538 (1.237-16.65) | .0226 |
| Group, N . | APS, 517 . | . | Control, 796 . | . | . | . |
|---|---|---|---|---|---|---|
| N | Incidence | N | Incidence | RR, 95%CI | P | |
| New pregnancies | 513 | 0.992 | 791 | 0.994 | ||
| Spontaneous abortions before 10 WG | 91 | 0.177 | 175 | 0.221 | 0.802 (0.639-1.007) | .0572 |
| Ongoing pregnancies at 10 WG | 422 | 0.823 | 621 | 0.785 | 1.048 (0.993-1.106) | .0917 |
| Fetal losses (% of new pregnancies) | 66 | 0.129 | 81 | 0.102 | 1.256 (0.926-1.705) | .143 |
| Fetal losses (% of ongoing pregnancies at 10 WG) | 66 | 0.156 | 81 | 0.130 | 1.199 (0.888-1.620) | .237 |
| Ongoing pregnancy at 20 WG (% of new pregnancies) | 387 | 0.754 | 567 | 0.717 | 1.052 (0.985-1.124) | .129 |
| Live births (% of new pregnancies) | 357 | 0.696 | 540 | 0.683 | 1.019 (0.946-1.098) | .613 |
| Live births (% of ongoing pregnancies at 10 WG) | 357 | 0.846 | 540 | 0.870 | 0.973 (0.925-1.024) | .289 |
| Preterm live births <37 WG (% of live births) | 89 | 0.249 | 74 | 0.137 | 1.819 (1.378-2.402) | <.0001 |
| Preterm live births <34 WG (% of live births) | 44 | 0.123 | 32 | 0.059 | 2.080 (1.346-3.214) | .0010 |
| PE (% of ongoing pregnancies at 20 WG) | 57 | 0.147 | 32 | 0.056 | 2.610 (1.726-4.550) | <.0001 |
| Severe PE | 40 | 0.103 | 21 | 0.037 | 2.791 (1.672-4.657) | .0001 |
| PE <34 WG | 38 | 0.098 | 15 | 0.026 | 3.712 (2.071-6.653) | <.0001 |
| Eclampsia | 12 | 0.031 | 8 | 0.014 | 2.198 (0.907-5.326) | .0813 |
| HELLP syndrome | 16 | 0.045 | 6 | 0.011 | 3.907 (1.543-9.896) | .0041 |
| SGA (% of ongoing pregnancies at 20 WG) | 73 | 0.395 | 80 | 0.141 | 1.337 (1,001-1;786) | .0495 |
| Severe SGA <p5 | 37 | 0.096 | 40 | 0.071 | 1.355 (0.883-2.079) | .164 |
| Very severe SGA <p3 | 26 | 0.067 | 25 | 0.044 | 1.524 (0.894-2.598) | .122 |
| PE + SGA | 39 | 0.100 | 20 | 0.035 | 2.857 (1.693-4.822) | .0001 |
| PA (% of ongoing pregnancies at 20 WG) | 12 | 0.031 | 11 | 0.019 | 1.598 (0.713-3.585) | .255 |
| Placenta-mediated complications: PE and/or SGA and/or PA (% of ongoing pregnancies at 20 WG) | 98 | 0.253 | 99 | 0.175 | 1.450 (1.132-1.858) | .0032 |
| NM (% of live births) | 18 | 0.047 | 8 | 0.014 | 3.529 (1.551-8.031) | .0026 |
| Early NM, day 1-7 | 9 | 0.023 | 5 | 0.009 | 2.723 (0.920-8.058) | .0704 |
| Late NM, day 8-27 | 9 | 0.023 | 3 | 0.005 | 4.538 (1.237-16.65) | .0226 |
95% CI, 95% confidence interval; NM, neonatal mortality; PA, placental abruption; RR, relative risk, APS women vs control women.