Demographic and clinical characteristics of patients with DLBCL by period of diagnosis in California, 1988-2009
| Characteristics . | Period of diagnosis, no. (%) . | P . | |
|---|---|---|---|
| 1988-2000, N = 16 899 . | 2001-2009, N = 16 133 . | ||
| Age at diagnosis, y | |||
| 75+ | 4 791 (28.4) | 4 984 (30.9) | <.01 |
| 65-74 | 4 354 (25.8) | 3 513 (21.8) | |
| 55-64 | 2 923 (17.3) | 3 100 (19.2) | |
| 45-54 | 2 087 (12.3) | 2 236 (13.9) | |
| 0-44 | 2 744 (16.2) | 2 300 (14.3) | |
| Race/ethnicity | |||
| Non-Hispanic white | 12 133 (71.8) | 9 950 (61.7) | <.01 |
| African Americans | 670 (4.0) | 718 (4.5) | |
| Hispanic | 2 556 (15.1) | 3 492 (21.6) | |
| Asian/Pacific Islander | 1 540 (9.1) | 1 973 (12.2) | |
| Sex | .54 | ||
| Male | 8 975 (53.1) | 8 623 (53.4) | |
| Female | 7 924 (46.9) | 7 510 (46.6) | |
| Marital status at diagnosis | <.01 | ||
| Married | 9 867 (58.4) | 8 998 (55.8) | |
| Never married | 2 281 (13.5) | 2 787 (17.3) | |
| Previously married | 4 279 (25.3) | 3 843 (23.8) | |
| Unknown | 472 (2.8) | 505 (3.1) | |
| Stage at diagnosis | <.01 | ||
| Localized | 4 760 (28.2) | 4 134 (25.6) | |
| Regional | 3 651 (21.6) | 3 347 (20.7) | |
| Advanced | 7 161 (42.4) | 7 552 (46.8) | |
| Unknown | 1 327 (7.9) | 1 100 (6.8) | |
| B symptoms | <.01 | ||
| Absent | 5 517 (32.6) | 7 916 (49.1) | |
| Present | 3 433 (20.3) | 4 283 (26.5) | |
| Unknown | 7 949 (47.0) | 3 934 (24.4) | |
| Nodal status | .13 | ||
| Nodal | 11 343 (67.1) | 10 703 (66.3) | |
| Extranodal | 5 556 (32.9) | 5 430 (33.7) | |
| Chemotherapy | .03 | ||
| No | 3 829 (22.7) | 3 805 (23.6) | |
| Yes | 12 717 (75.3) | 12 036 (74.6) | |
| Unknown | 353 (2.1) | 292 (1.8) | |
| Radiation | <.01 | ||
| No | 12 112 (71.7) | 12 671 (78.5) | |
| Yes | 4 784 (28.3) | 3 460 (21.4) | |
| Unknown | <5 | <5 | |
| Treated at an NCI-designated hospital | <.01 | ||
| No | 15 671 (92.7) | 14 637 (90.7) | |
| Yes | 1 227 (7.3) | 1 495 (9.3) | |
| Unknown | <5 | <5 | |
| Urbanicity | |||
| Urban | 11 298 (66.9) | 10 409 (64.5) | |
| Nonurban | 4 930 (29.2) | 5 243 (32.5) | |
| Unknown | 671 (4.0) | 481 (3.0) | <.01 |
| Neighborhood SES quintile | .62 | ||
| 1. Lowest 20% | 2 385 (14.1) | 2 374 (14.7) | |
| 2 | 3 073 (18.2) | 2 940 (18.2) | |
| 3 | 3 530 (20.9) | 3 349 (20.8) | |
| 4 | 3 804 (22.5) | 3 581 (22.2) | |
| 5. Highest 20% | 4 107 (24.3) | 3 889 (24.1) | |
| Characteristics . | Period of diagnosis, no. (%) . | P . | |
|---|---|---|---|
| 1988-2000, N = 16 899 . | 2001-2009, N = 16 133 . | ||
| Age at diagnosis, y | |||
| 75+ | 4 791 (28.4) | 4 984 (30.9) | <.01 |
| 65-74 | 4 354 (25.8) | 3 513 (21.8) | |
| 55-64 | 2 923 (17.3) | 3 100 (19.2) | |
| 45-54 | 2 087 (12.3) | 2 236 (13.9) | |
| 0-44 | 2 744 (16.2) | 2 300 (14.3) | |
| Race/ethnicity | |||
| Non-Hispanic white | 12 133 (71.8) | 9 950 (61.7) | <.01 |
| African Americans | 670 (4.0) | 718 (4.5) | |
| Hispanic | 2 556 (15.1) | 3 492 (21.6) | |
| Asian/Pacific Islander | 1 540 (9.1) | 1 973 (12.2) | |
| Sex | .54 | ||
| Male | 8 975 (53.1) | 8 623 (53.4) | |
| Female | 7 924 (46.9) | 7 510 (46.6) | |
| Marital status at diagnosis | <.01 | ||
| Married | 9 867 (58.4) | 8 998 (55.8) | |
| Never married | 2 281 (13.5) | 2 787 (17.3) | |
| Previously married | 4 279 (25.3) | 3 843 (23.8) | |
| Unknown | 472 (2.8) | 505 (3.1) | |
| Stage at diagnosis | <.01 | ||
| Localized | 4 760 (28.2) | 4 134 (25.6) | |
| Regional | 3 651 (21.6) | 3 347 (20.7) | |
| Advanced | 7 161 (42.4) | 7 552 (46.8) | |
| Unknown | 1 327 (7.9) | 1 100 (6.8) | |
| B symptoms | <.01 | ||
| Absent | 5 517 (32.6) | 7 916 (49.1) | |
| Present | 3 433 (20.3) | 4 283 (26.5) | |
| Unknown | 7 949 (47.0) | 3 934 (24.4) | |
| Nodal status | .13 | ||
| Nodal | 11 343 (67.1) | 10 703 (66.3) | |
| Extranodal | 5 556 (32.9) | 5 430 (33.7) | |
| Chemotherapy | .03 | ||
| No | 3 829 (22.7) | 3 805 (23.6) | |
| Yes | 12 717 (75.3) | 12 036 (74.6) | |
| Unknown | 353 (2.1) | 292 (1.8) | |
| Radiation | <.01 | ||
| No | 12 112 (71.7) | 12 671 (78.5) | |
| Yes | 4 784 (28.3) | 3 460 (21.4) | |
| Unknown | <5 | <5 | |
| Treated at an NCI-designated hospital | <.01 | ||
| No | 15 671 (92.7) | 14 637 (90.7) | |
| Yes | 1 227 (7.3) | 1 495 (9.3) | |
| Unknown | <5 | <5 | |
| Urbanicity | |||
| Urban | 11 298 (66.9) | 10 409 (64.5) | |
| Nonurban | 4 930 (29.2) | 5 243 (32.5) | |
| Unknown | 671 (4.0) | 481 (3.0) | <.01 |
| Neighborhood SES quintile | .62 | ||
| 1. Lowest 20% | 2 385 (14.1) | 2 374 (14.7) | |
| 2 | 3 073 (18.2) | 2 940 (18.2) | |
| 3 | 3 530 (20.9) | 3 349 (20.8) | |
| 4 | 3 804 (22.5) | 3 581 (22.2) | |
| 5. Highest 20% | 4 107 (24.3) | 3 889 (24.1) | |