Poisson regression models for reported cancers and autoimmune diseases after donation
| Variable . | n . | Number of events . | Relative risk . | 95% confidence interval . | P . |
|---|---|---|---|---|---|
| Cancer (excluding nonmelanoma skin cancer) | |||||
| Product | |||||
| PBSC | 6768 | 29 | 1.00 | ||
| BM | 2726 | 11 | 0.91 | 0.45-1.82 | .792 |
| Age at donation, years | <.001 | ||||
| 18-39 | 6147 | 12 | 1.00 | ||
| 40-49 | 2413 | 16 | 3.26 | 1.54-6.90 | .002 |
| 50+ | 934 | 12 | 6.42 | 2.87-14.35 | <.001 |
| BMI, kg/m2 | .042 | ||||
| <24.5 | 2850 | 16 | 1.00 | ||
| 25-29.5 | 3703 | 9 | 0.37 | 0.17-0.85 | .019 |
| ≥30 | 2940 | 15 | 0.79 | 0.39-1.59 | .503 |
| Nonmelanoma skin cancer | |||||
| Product | |||||
| PBSC | 6768 | 23 | 1.00 | ||
| BM | 2726 | 11 | 1.20 | 0.58-2.46 | .624 |
| Age at donation, years | <.001 | ||||
| 18-39 | 6147 | 11 | 1.00 | ||
| 40-49 | 2413 | 13 | 2.82 | 1.26-6.30 | .011 |
| 50+ | 934 | 10 | 6.14 | 2.60-14.48 | <.001 |
| Donor cytomegalovirus | |||||
| Negative | 5678 | 27 | 1.00 | ||
| Positive | 3814 | 7 | 0.36 | 0.16-0.84 | .018 |
| Autoimmune diseases | |||||
| Product | |||||
| PBSC | 6768 | 35 | 1.00 | ||
| BM | 2726 | 11 | 0.79 | 0.40-1.55 | .484 |
| Sex | |||||
| Female | 3686 | 29 | 1.00 | ||
| Male | 5808 | 17 | 0.38 | 0.21-0.69 | .001 |
| Race | |||||
| White | 7018 | 41 | 1.00 | ||
| Other | 2476 | 5 | 2.67 | 1.05-6.77 | .039 |
| Age at donation, years | .009 | ||||
| 18-39 | 6147 | 20 | 1.00 | ||
| 40-49 | 2413 | 14 | 1.49 | 0.75-2.95 | .267 |
| 50+ | 934 | 12 | 3.33 | 1.62-6.82 | <.001 |
| Variable . | n . | Number of events . | Relative risk . | 95% confidence interval . | P . |
|---|---|---|---|---|---|
| Cancer (excluding nonmelanoma skin cancer) | |||||
| Product | |||||
| PBSC | 6768 | 29 | 1.00 | ||
| BM | 2726 | 11 | 0.91 | 0.45-1.82 | .792 |
| Age at donation, years | <.001 | ||||
| 18-39 | 6147 | 12 | 1.00 | ||
| 40-49 | 2413 | 16 | 3.26 | 1.54-6.90 | .002 |
| 50+ | 934 | 12 | 6.42 | 2.87-14.35 | <.001 |
| BMI, kg/m2 | .042 | ||||
| <24.5 | 2850 | 16 | 1.00 | ||
| 25-29.5 | 3703 | 9 | 0.37 | 0.17-0.85 | .019 |
| ≥30 | 2940 | 15 | 0.79 | 0.39-1.59 | .503 |
| Nonmelanoma skin cancer | |||||
| Product | |||||
| PBSC | 6768 | 23 | 1.00 | ||
| BM | 2726 | 11 | 1.20 | 0.58-2.46 | .624 |
| Age at donation, years | <.001 | ||||
| 18-39 | 6147 | 11 | 1.00 | ||
| 40-49 | 2413 | 13 | 2.82 | 1.26-6.30 | .011 |
| 50+ | 934 | 10 | 6.14 | 2.60-14.48 | <.001 |
| Donor cytomegalovirus | |||||
| Negative | 5678 | 27 | 1.00 | ||
| Positive | 3814 | 7 | 0.36 | 0.16-0.84 | .018 |
| Autoimmune diseases | |||||
| Product | |||||
| PBSC | 6768 | 35 | 1.00 | ||
| BM | 2726 | 11 | 0.79 | 0.40-1.55 | .484 |
| Sex | |||||
| Female | 3686 | 29 | 1.00 | ||
| Male | 5808 | 17 | 0.38 | 0.21-0.69 | .001 |
| Race | |||||
| White | 7018 | 41 | 1.00 | ||
| Other | 2476 | 5 | 2.67 | 1.05-6.77 | .039 |
| Age at donation, years | .009 | ||||
| 18-39 | 6147 | 20 | 1.00 | ||
| 40-49 | 2413 | 14 | 1.49 | 0.75-2.95 | .267 |
| 50+ | 934 | 12 | 3.33 | 1.62-6.82 | <.001 |